Recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp), more appropriately called as stress response proteins (srp). hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.

Type: Primary
Antigen: HSPD1
Clonality: Monoclonal
Clone: HSPD1/875
Conjugation: CF568
Epitope:
Host: Mouse
Reactivity: Chicken, Guinea Pig, Hamster, Human, Monkey, Mouse, Pig, Rat
Isotype: IgG1, kappa