Recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Type: Primary
Antigen: CR1
Clonality: Monoclonal
Clone: CR1/802
Conjugation: CF594
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Human, Monkey
- Catalog No:
- BNC940802-500
- BNC940802-100
- Antigen symbol:
- CR1
- CR1
- Antigen name:
- CD35 / CR1
- CD35 / CR1
- Antigen synonyms:
- C3BR|Complement Component (3b/4b) receptor 1 including Knops blood group system|C3b/C4b receptor|KN|C3 binding protein|Knops blood group antigen|Complement receptor type 1|C4BR
- C3BR|Complement Component (3b/4b) receptor 1 including Knops blood group system|C3b/C4b receptor|KN|C3 binding protein|Knops blood group antigen|Complement receptor type 1|C4BR
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 594
- CF® 594
- Clone:
- Clone CR1/802
- Clone CR1/802
- Reactivity:
- Baboon, Monkey, Human
- Baboon, Monkey, Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 334019
- 334019
- Isotype:
- IgG1 kappa
- IgG1 kappa
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide