About this item
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Type: Primary
Antigen: IGL
Clonality: Monoclonal
Clone: LcN-2
Conjugation: CF405S
Epitope:
Host: Mouse
Isotype: IgG2a, kappa
Reactivity: Human
Specifications
- Catalog No:
- BNC040631-100
- BNC040631-500
- Antigen symbol:
- IGL
- IGL
- Antigen name:
- Lambda Light Chain
- Lambda Light Chain
- Antigen synonyms:
- Paraprotein|BJP|Mcg Marker|Bence Jones Protein|IGLC 1/2/3
- Paraprotein|BJP|Mcg Marker|Bence Jones Protein|IGLC 1/2/3
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- CF® 405S
- CF® 405S
- Clone:
- Clone LcN-2
- Clone LcN-2
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- 449585
- 449585
- Isotype:
- IgG2a kappa
- IgG2a kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifications
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: HEATHROW
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Chemicals
Supplier: VWR Collection
Supplier: VWR Collection
Supplier: KIMBERLY CLARK
Supplier: VWR Collection