Anti-RPE65 Rabbit Polyclonal Antibody (Cy5®)

Catalog # BOSSBS-9575R-CY5

Supplier: Bioss

Catalog # BOSSBS-9575R-CY5

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
Retinal Pigment Epithelium-specific 65 kDa protein
Antigen symbol:
RPE65
Clonality:
Polyclonal
Conjugation:
Cy5®
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Antigen synonyms:
sRPE65|all-trans-retinyl-palmitate hydrolase|retinol isomerase|retinoid isomerohydrolase|retinitis pigmentosa 20 (autosomal recessive)|retinal pigment epithelium-specific 65 kDa protein|RBP-binding membrane protein|p63|LCA2|RP20|rd12|mRPE65
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at –20 °C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

The retinal pigment epithelium (RPE) is a monolayer simple epithelium in proximity to the outer surface of the retinal photoreceptor cells. Retinal pigment epithelium-specific protein (RPE65) is a 65 kDa protein belonging to the Î²-carotene dioxygenase family. This protein is important in 11-cis retinal production as well as in visual pigment regeneration. RPE65 is attached to the membrane by a lipid anchor when palmitoylated (membrane form) and soluble when unpalmitoylated. The soluble form of the protein binds vitamin A. Defects in RPE65 causes autosomal dominant retinitis pigmentosa and/or Leber congenital amaurosis type 2.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: RPE65
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat