- Antibody type:Primary
- Antigen name:GALNT1/GalNAc-T1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Epitope:101-200/559
- Form:Liquid
- Gene ID:2589
- Antigen synonyms:UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1|Polypeptide N acetylgalactosaminyltransferase 1|GALNAC T1|Polypeptide GalNAc transferase 1|GALT1_HUMAN|Protein-UDP acetylgalactosaminyltransferase 1|UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 GalNAc T1|GalNAc transferase 1|Protein UDP acetylgalactosaminyltransferase 1|UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 1|pp-GaNTase 1|GALNT1|GalNAc-T1|Polypeptide N-acetylgalactosaminyltransferase 1 soluble form|GALNT 1|pp GaNTase 1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:64 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human GALNT1/GalNAc-T1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked oligosaccharide biosynthesis, namely the transfer of an N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses calcium and manganese as cofactors. Due to alternative splicing events, two GalNAc-T1 isoforms are expressed.
Type: Primary
Antigen: GALNT1/GalNAc-T1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/559
Host: Rabbit
Isotype: IgG
Reactivity: