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Anti-FANCD2 Mouse Monoclonal Antibody [clone: FI-17]
  PIEAMA116570
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Anti-FANCD2 Mouse Monoclonal Antibody [clone: FI-17]
  PIEAMA116570

 

  • Antibody type:
    Primary
  • Antigen name:
    Fanconi Anemia Complementation Group D2
  • Antigen symbol:
    FANCD2
  • Clonality:
    Monoclonal
  • Clone:
    FI-17
  • Conjugation:
    Unconjugated
  • Host:
    Mouse
  • ImmunoPrecipitation:
    Yes
  • Reactivity:
    Human
  • Western blot:
    Yes
  • ChIP:
    Yes
  • Format:
    ascites
  • Form:
    Liquid
  • Gene ID:
    2177
  • Antigen synonyms:
    FANCONI PANCYTOPENIA TYPE 4|FAD|FA4|FANCD|FANCONI ANEMIA COMPLEMENTATION GROUP D|FACD|FAD2
  • Storage buffer:
    ascites, 0.1% sodium azide
  • Storage temperature:
    -20° C, Avoid Freeze/Thaw Cycles
  • Shipping temperature:
    Ice
  • Immunogen:
    FANCD2 fusion protein
  • Size:
    100 µL
  • Pk:
    100 µl

 

 

By Western blot, this antibody recognizes a band at ~155 and ~162 kDa (post-translationally modified form). Suggested positive control: Hela whole cell extract. Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein.

Type: Primary
Antigen: FANCD2
Clonality: Monoclonal
Clone: FI-17
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human