Specifications
- Antibody type:Primary
- Antigen name:cyclin-dependent kinase 5
- Antigen symbol:CDK5
- Clonality:Monoclonal
- Clone:8A1
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoPrecipitation:Yes
- Isotype:IgG2b
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:none
- Gene ID:1020
- Antigen synonyms:PSSALRE|LIS7
- Storage temperature:Store for 1 year at –20 °C from date of shipment
- Shipping temperature:Ice
- Immunogen:His-tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells.
- Purification:Ammonium sulfate precipitation
- Size:100 µl
- Pk:0,1 mL
Specifications
About this item
Cyclin-dependent kinase-5 (CDK5) is a member of the cyclin-dependent kinase family of serine/threonine kinases. Its mRNA and protein are expressed in kidney, testes, and ovary. And Its activity is detected almost exclusively in brain extracts.
Similar to other Cdks, monomeric Cdk5 displays no enzymatic activity, but Cdk5 is not activated by cyclins. Instead, Cdk5 activity requires association with one of two brain-specific regulatory subunits called p35 and p39. The two activators regulate the spatial and temporal expression of active Cdk5 to restrict its activity primarily to post-mitotic neurons.
Western Blot: 1:1000 ~ 2000; Immunoprecipitation: 2 ?l;
Type: Primary
Antigen: CDK5 (cyclin-dependent kinase 5)
Clonality: Monoclonal
Clone: 8A1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human, Mouse, Rat