- Antibody type:Primary
- Antigen name:phospholipase C, gamma 1
- Antigen symbol:PLCG1
- Clonality:Monoclonal
- Clone:2B1
- Conjugation:Unconjugated
- Host:Mouse
- ImmunoPrecipitation:Yes
- Isotype:IgG2a
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:none
- Gene ID:5335
- Antigen synonyms:PLCgamma1|PLC1|PLC148|NCKAP3|PLC-II
- Storage temperature:Store for 1 year at –20 °C from date of shipment
- Concentration:1 mg/ml
- Shipping temperature:Ice
- Immunogen:Recombinant human protein purified from E.coli
- Purification:Protein G purified
- Size:100 µl
- Pk:0,1 mL
The mammalian Phospholipase C(PLC) family has two closely related proteins, PLC1 and PLC2. The PLC isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLC. Activated PLC catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
Western Blot: 0.1 ?g/ml; Immunoprecipitation: 1.0 ?g;
Type: Primary
Antigen: PLCG (phospholipase C gamma)
Clonality: Monoclonal
Clone: 2B1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a Kappa
Reactivity: Human, Mouse, Rat