You searched for: Proteins and Peptides

Supplier: MP Biomedicals

Albumins are a group of acidic proteins which occur in the body fluids and tissues of mammals and in some plant seeds. Serum and plasma albumin is carbohydrate-free and comprises 55 to 62% of the protein present. However, only about 40% of the total albumin in the body is in the circulating plasma at one time with the remainder being in extracellular spaces with which there is, in general, equilibration about every 24 hours.

Supplier: MP Biomedicals

Streptavidin is soluble in water at 1 mg/ml (clear to hazy), or in phosphate buffered saline (PBS). Readily soluble in water or salt-containing buffers (50 mg/ml or more).

Supplier: MP Biomedicals

Cytochrome C is an electron-carrying mitochondrial protein. The transition of Cytochrome C between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen.

Supplier: MP Biomedicals

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. It functions as a carrier protein for steroids, fatty acids, and thyroid hormones.

Supplier: MP Biomedicals

Laminin is purified from basement membrane matrix derived from Engelbreth-Holm- Swarm (EHS) mouse sarcoma. It is > 95% pure by SDS-PAGE.

Supplier: MP Biomedicals

Reconstitution: Reconstitute with water to a final concentration of 1 mg/ml (use 1 ml for the 1 mg size or 5 ml for the 5 mg size) for a final solution of 1 mg/ml in 0,40 mM sodium phosphate, 6 mM NaCl, pH 7,45. Reconstitute with water to a final concentration of 25 mg/ml (0,2 ml water for the 5 mg size). This concentration of the lectin has been used for iontophoresis and neuron transport.

Supplier: EDQM

Human albumin (from serum)

Supplier: MP Biomedicals

Leupeptin is a modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin8 and plasmin.

Supplier: MP Biomedicals

Concanavalin A is a pure Canavalia ensiformis lectin, FITC conjugated proteins or glycoproteins of non-immune origin that agglutinate cells and precipitate complex carbohydrates. They are capable of binding glycoproteins even in presence of various detergents.

Supplier: MP Biomedicals

Z-Val-Ala-Asp-(Ome)-fluoromethylketone

Supplier: MP Biomedicals

Glycylglycine is a dipeptide and is the simplest of all dipeptides.

Supplier: MP Biomedicals

Follicle stimulating hormone is a two-chain glycoprotein gonadotropic hormone that induces maturation of the Graafian follicles of the ovary. It promotes the development of germinal cells in males. It regulates sertoli cells by acting on G-protein-linked cell surface FSH receptors. It activates cytosolic soluble protein tyrosine kinase (CyPTk).

Supplier: MP Biomedicals

Lectins are proteins or glycoproteins of non-immune origin that agglutinate cells and/or precipitate complex carbohydrates. They are capable of binding glycoproteins even in presence of various detergents. The agglutination activity of these highly specific carbohydrate-binding molecules is usually inhibited by a simple monosaccharide, but for some lectins, di, tri, and even polysaccharides are required.

Supplier: MP Biomedicals

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. It stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.

Supplier: MP Biomedicals

Phytohemagglutinin lectin is isolated from red kidney bean (Phaseolus vulgaris). This product is a partially purified product consisting of a mixture of isolectins. PHA will agglutinate erythrocytes of all human blood groups and many mammal.

Supplier: MP Biomedicals

Aspartame is a synthetic and low-calorie sweetener and is used as an active ingredient in consumer foods, beverages, soft drinks, breath mints, sugar free chewing gum, cocoa mixes, frozen desserts, chewable vitamin supplements, milk drinks, cereals, pharmaceutical drugs and supplements, tabletop sweeteners and diet sodas.

Supplier: MP Biomedicals

Thrombin is used throughout the diagnostics industry in a variety of coagulation assays, clotting factor tests and defibrination of blood or plasma for serum controls. It is also used for site specific cleavage of recombinant fusion proteins, and in biochemical and medical research applications. It is manufactured from New Zealand-sourced bovine plasma using prothrombin activated with thromboplastin extracted from bovine lung tissue.

Supplier: MP Biomedicals

MP offers this grade of albumin as a more highly purified product than our traditional True Cohn Fraction V Powder. This grade of albumin also varies in its fatty acids content (1 to 2 mg/gm). Due to lower manufacturing costs, this grade is available at a substantial savings relative to our True Cohn Fraction V Powder.

Supplier: MP Biomedicals

Avidin is a basic glycoprotein consisting of four essentially identical subunits. The combined molecular weight of the subunits is about 66,000. Each subunit is a single polypeptide chain containing 128 amino acid residues with alanine at the N-terminal, glutamic acid at the C-terminal, and a carbohydrate moiety attached at the aspariginyl residue, position 17. It is isolated from raw egg white. It exhibits high binding affinity for biotin and is capable of producing biotin deficiency in rats and chicks. It also occurs in the white portion of eggs and the oviducts of birds and amphibia. It is destroyed by cooking or irradiation.

Supplier: MP Biomedicals

Fibrinogen is a blood protein that is involved in clotting and is converted to fibrin by thrombin. Fibrinogen has an approximate molecular weight of 340 kDa. It consists of three non-identical pairs of disulfidebonded chains. The α-chain has an approximate molecular weight of 63,5 kDa, the β-chain 56 kDa, and the γ-chain 47 kDa. At the amino termini, the three chains are connected in a dimeric disulfide knot (DSK). A second DSK occurs later in the molecule. Fibrinogen has approximately 4% carbohydrate content.

Supplier: MP Biomedicals

Below 35 to 40 °C gelatin swells and absorbs approximately 5 to 10 times its weight of water to form a gel. Gelatin is soluble in glycerol and acetic acid, and more soluble in hot than in cold water. It is practically insoluble in most organic solvents such as alcohol, chloroform, carbon disulphide, carbon tetrachloride, ether, benzene, acetone and oils. Sterile solutions of gelatin stored cold are stable indefinitely, but at elevated temperatures hydrolysis or rupture of peptide bonds occurs, increasing the number of free amino groups. Gel strength and viscosity gradually weaken upon prolonged heating in solution above ~40 °C; this degradation is accelerated by extremes in pH, proteolytic enzymes and bacterial action.

Supplier: MP Biomedicals

Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. It exists as a dimer below pH 5,0 and and at pH >7 it exists as a tetramer. It is a metalloprotein and requires a transition metal ion, such as manganese, plus calcium ions for binding.

Supplier: MP Biomedicals

Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-L-lysine increases the number of positively charged sites available for cell binding. Polymers of both D- and L-lysine are used to coat solid surfaces.

Supplier: MP Biomedicals

Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.

Supplier: MP Biomedicals

A modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin and plasmin. Little to no inhibition is seen against pepsin, cathepsins A and D and alpha-chymotrypsin. When adjusted for molarity, all three salt forms are equally effective; however, the hydrochloride salt is usually less invasive in biological settings. Leupeptin, because of its aldehyde group, may act as a reducing agent and therefore interfere in protein determinations such as Lowry and, to a lesser extent, Bradford.

Supplier: MP Biomedicals

C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. It is composed of 18 polypeptide chains (six A, six B, six C). All contain an 81 amino acid collagen like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.

Supplier: MP Biomedicals

Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.

Supplier: MP Biomedicals

CellMaxx™ Bovine Transferrin is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. Transferrin (HOLO) is an iron-rich product supplied as a heat-treated, lyophilised powder.

Supplier: MP Biomedicals

Collagen is Type I soluble, salt free component of skin, bone, tendon, and other fibrous connective tissues. Type I collagen differs from other collagens by their low lysine hydroxylation and low carbohydrate composition. It breaks down metabolically in the body to release N-telopeptide, which is the N-terminus of collagen. There is also C-telopeptide, which is presumably the C-terminus. N-telopeptide is released in urine, and its detection in diagnostic tests is used to screen for osteoporosis.

Supplier: MP Biomedicals

E-64 is an inhibitor for thiol protease, papain, actinidin, ananain, bromelain, calpain and cathepsin B. An irreversible cysteine protease inhibitor that has no action on cysteine residues in other plants. It does not react with low molecular weight thiols such as 2-mercaptoethanol.