You searched for: Proteins and Peptides

Supplier: MP Biomedicals

Z-Val-Ala-Asp-(Ome)-fluoromethylketone

Supplier: MP Biomedicals

Pure Canavalia ensiformis lectin (Con A) from Jackbean. Isolated by affinity chromatography on cross-linked dextran. It exists as a dimer below pH 5,0 and and at pH >7 it exists as a tetramer. It is a metalloprotein and requires a transition metal ion, such as manganese, plus calcium ions for binding.

Supplier: MP Biomedicals

Concanavalin A is a pure Canavalia ensiformis lectin, FITC conjugated proteins or glycoproteins of non-immune origin that agglutinate cells and precipitate complex carbohydrates. They are capable of binding glycoproteins even in presence of various detergents.

Supplier: MP Biomedicals

Glycylglycine is a dipeptide and is the simplest of all dipeptides.

Supplier: MP Biomedicals

Fibrinogen is a blood protein that is involved in clotting and is converted to fibrin by thrombin. Fibrinogen has an approximate molecular weight of 340 kDa. It consists of three non-identical pairs of disulfidebonded chains. The α-chain has an approximate molecular weight of 63,5 kDa, the β-chain 56 kDa, and the γ-chain 47 kDa. At the amino termini, the three chains are connected in a dimeric disulfide knot (DSK). A second DSK occurs later in the molecule. Fibrinogen has approximately 4% carbohydrate content.

Supplier: MP Biomedicals

Aspartame is a synthetic and low-calorie sweetener and is used as an active ingredient in consumer foods, beverages, soft drinks, breath mints, sugar free chewing gum, cocoa mixes, frozen desserts, chewable vitamin supplements, milk drinks, cereals, pharmaceutical drugs and supplements, tabletop sweeteners and diet sodas.

Supplier: MP Biomedicals

Below 35 to 40 °C gelatin swells and absorbs approximately 5 to 10 times its weight of water to form a gel. Gelatin is soluble in glycerol and acetic acid, and more soluble in hot than in cold water. It is practically insoluble in most organic solvents such as alcohol, chloroform, carbon disulphide, carbon tetrachloride, ether, benzene, acetone and oils. Sterile solutions of gelatin stored cold are stable indefinitely, but at elevated temperatures hydrolysis or rupture of peptide bonds occurs, increasing the number of free amino groups. Gel strength and viscosity gradually weaken upon prolonged heating in solution above ~40 °C; this degradation is accelerated by extremes in pH, proteolytic enzymes and bacterial action.

Supplier: MP Biomedicals

Thrombin is used throughout the diagnostics industry in a variety of coagulation assays, clotting factor tests and defibrination of blood or plasma for serum controls. It is also used for site specific cleavage of recombinant fusion proteins, and in biochemical and medical research applications. It is manufactured from New Zealand-sourced bovine plasma using prothrombin activated with thromboplastin extracted from bovine lung tissue.

Supplier: MP Biomedicals

MP offers this grade of albumin as a more highly purified product than our traditional True Cohn Fraction V Powder. This grade of albumin also varies in its fatty acids content (1 to 2 mg/gm). Due to lower manufacturing costs, this grade is available at a substantial savings relative to our True Cohn Fraction V Powder.

Supplier: MP Biomedicals

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. It stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.

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Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-L-lysine increases the number of positively charged sites available for cell binding. Polymers of both D- and L-lysine are used to coat solid surfaces.

Supplier: MP Biomedicals

Collagen is Type I soluble, salt free component of skin, bone, tendon, and other fibrous connective tissues. Type I collagen differs from other collagens by their low lysine hydroxylation and low carbohydrate composition. It breaks down metabolically in the body to release N-telopeptide, which is the N-terminus of collagen. There is also C-telopeptide, which is presumably the C-terminus. N-telopeptide is released in urine, and its detection in diagnostic tests is used to screen for osteoporosis.

Supplier: MP Biomedicals

Poly-L-lysine is a positively charged amino acid polymer. Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding.

Supplier: MP Biomedicals

C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. It is composed of 18 polypeptide chains (six A, six B, six C). All contain an 81 amino acid collagen like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.

Supplier: MP Biomedicals

Soluble in acetic acid 80% (50 mg/ml - clear colourless solution)

Supplier: MP Biomedicals

Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.

Supplier: MP Biomedicals

CellMaxx™ Bovine Transferrin is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. Transferrin (HOLO) is an iron-rich product supplied as a heat-treated, lyophilised powder.

Supplier: MP Biomedicals

E-64 is an inhibitor for thiol protease, papain, actinidin, ananain, bromelain, calpain and cathepsin B. An irreversible cysteine protease inhibitor that has no action on cysteine residues in other plants. It does not react with low molecular weight thiols such as 2-mercaptoethanol.

Supplier: MP Biomedicals

A modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin and plasmin. Little to no inhibition is seen against pepsin, cathepsins A and D and alpha-chymotrypsin. When adjusted for molarity, all three salt forms are equally effective; however, the hydrochloride salt is usually less invasive in biological settings. Leupeptin, because of its aldehyde group, may act as a reducing agent and therefore interfere in protein determinations such as Lowry and, to a lesser extent, Bradford.

Supplier: MP Biomedicals

Lipoprotein- cholesterol is a mixture of lipoprotein cholesterol, phospholipids and fatty acids.

Supplier: MP Biomedicals

Soluble in 1:1 CHCl₃:methanol (50 mg/ml), soluble in DMF ((25 mg/ml).

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Typically prepared as a suspension in water adjusted to pH 5,0 with acetic acid. A 1% w/v solution will appear turbid.

Supplier: MP Biomedicals

Casein from bovine milk is a phosphoprotein. It make up approximately 80% of the total protein in bovine milk. It is proposed to be the main protective constituent in milk.

Supplier: MP Biomedicals

Phytohemagglutinin PHA agglutinates the erythrocytes of all human blood groups as well as those of rabbit, dog, cat, mouse, sheep, and guinea pig.

Supplier: MP Biomedicals

There is approximately one HBr or HCl per lysine unit. The HBr/HCl allows it to be a crystalline solid and soluble in water. To remove the HBr/HCl, solubilise the product in a neutral buffer and dialyse away the salts.

Supplier: MP Biomedicals

Chymostatin ([(S)-1-Carboxy-2-phenylethyl]-carbamoyl-α-[2-iminohexahydro-4(S)-pyrimidyl]-(S)-Gly-X-Phe-al) Source/Species: Microbial A mixture of type A, B, and C. X = Leu (Type A); Ile (Type B); Val (Type C). Ref: 1. Umezawa, H., et al., J. Antibiot., 23: 425 (1970). 2. Tatsuta, K., et al., J. Antibiot., 26: 625 (1973).

Supplier: MP Biomedicals

Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.

Supplier: MP Biomedicals

Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes with, and blocks the active sites of serine protease enzymes. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.
Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3.

Aprotinin is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones.

Supplier: MP Biomedicals

AlbumiNZ™ Low Fatty Acid BSA is chromatographically purified from New Zealand-sourced bovine plasma in an ISO quality system assuring complete traceability and consistent high quality. This albumin has very low endotoxin and low free fatty acids, is tested for the absence of viruses according to 9CFR and has the highest possible biosafety level.

Supplier: MP Biomedicals

Gelatin is a heterogeneous mixture of water-soluble proteins of high average molecular weights, present in collagen. The proteins are extracted by boiling skin, tendons, ligaments, bones, etc. in water. Type A gelatin is derived from acid hydrolysed tissue. The charge on a gelatin molecule and its isoelectric point are primarily due to the carboxyl amino and guanidino groups on the side chains. Type A gelatin has 78 to 80 millimoles of free carboxyl groups per 100 g of protein and a pI of 7,0 to 9,0.