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Genomics

Genomics Tools, Solutions and Resources

Genomics, or the study of human genes and chromosomes, enables scientists to learn more about a patient's molecular biology. This field of science has enormous potential to reshape drug discovery and development by leading the drive to personalized medicine. Whether you are working on advancing gene therapies or personalized medicine or using genomics tools and technologies for next-generation sequencing and genome editing, Avantor® offers a wide range of genomic tools and solutions to pave the way for your scientific goals to be met.

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Learn more about how we can help you stock up with everything you need for genomics in your laboratory.

Contact us today to discuss your needs. Our team is ready to help.

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Featured Content

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Everything you need for Quantitative Real-Time Polymerase Chain Reaction (qPCR) – a technique that monitors the enzymatic amplification of a targeted sequence of DNA.

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A variety of products for mutagenesis, restriction cloning, synthetic biology, CRISPR/Cas9 and more.

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A wide selection of next generation sequencing (NGS) products that help researchers sequence millions of DNA molecules simultaneously.

Nucleic Acid Purification and Measurement

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DNA samples are purified by lysating (bursting or cutting) a cell or cell structure from desired samples using lab procedures to isolate the nucleic acids from its contaminants. Purifying DNA samples from contaminants also extends their shelf-life and reduces the probability of error when it comes to research results.

Avantor can help you source high-quality nucleic acid purification systems that are simple to operate and generate rapid results. Here are some choices below.

Get the automated nucleic acid purification systems you need for your lab

Robust, compact, high-value microplate readers for all your biological assays

Kits and reagents for the preparation of DNA/RNA libraries for NGS

DNA/RNA clean-up reagents and kits to prepare your samples for downstream applications.

Reagents and kits to isolate genomic DNA.

Reagents and kits to isolate plasmid DNA.

RNA purification solutions including reagents, kits and accessories.

Manual or automated benchtop homogenizers have user-friendly control systems for straightforward processing.

IR and FTIR spectrophotometers are available at Avantor to meet your research needs.

Selection of cleaning agents to remove, inactivate, or completely destroy contaminants.

Amplification

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To study or detect individual genes or specific DNA of interest, obtaining a large quantity of nucleic acid for study is often necessary. Rather than isolate a single copy of the target DNA from a large number of cells, it is often more useful to generate multiple copies of a target from a single molecule of DNA or mRNA, via an in vitro amplification method.

Polymerase Chain Reaction (PCR) is the most common DNA amplification method in molecular biology, Avantor’s product portfolio features a large selection of Genomic tools, solutions and resources geared towards this powerful method. Review a variety of genomics resources below that can deliver successful amplification for your lab’s research.

See our broad range of centrifuges for PCR applications and more.

We offer a variety of End-point PCR reagents and kits.

Filters will block aerosol contaminants to protect both the equipment and sample.

Broad range of microplate sealing films and foils to reduce evaporation during reactions.

Kits and reagents for the preparation of DNA/RNA libraries for NGS

View our wide selection of high-purity Nucleotides.

We offer an extensive variety of PCR Plates.

See our thermal cyclers for PCR and qPCR applications.

Discover our large selection of high-quality PCR tubes.

PCR workstation enclosures provide the contamination-free environment required for the most sensitive DNA segment detection.

Selected primers and probes for cDNA synthesis, sequencing and hybridization applications.

Get all the reagents you need for qPCR.

Racks to store PCR tubes and prepare your PCR reactions.

Reagents and kits for Reverse Transcription PCR and cDNA synthesis

Sequencing in Genomic Life Sciences

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Sequencing is considered to be the “gold standard” method for the identification of known (as well as unspecified) variants in genomic DNA.

Broadly speaking, there are two types of DNA sequencing: shotgun and high-throughput. Shotgun (Sanger) sequencing is the more traditional approach, which is designed for the entire sequencing of chromosomes or long DNA strands with more than 1000 base pairs. It involves a rapidly expanding firing pattern to read the DNA in short fragments of 100 to 1000 base pairs, which are then overlapped with a computer analysis system.

High-throughput is the next-generation method of DNA sequencing (NGS), which has led to the rapid acceleration of DNA sequencing and broadened knowledge in the field. It can produce thousands of sequences simultaneously, which significantly lowers the cost of the technique.

Sequencing supplies from industry leaders are available, affordable and easy to use whether your lab utilizes Sanger Sequencing or Next-Generation Sequencing. Our tools and resources can help.

See or range of nanopore DNA/RNA sequencing devices.

Flow cells needed for nanopore sequencing devices.

Kits and reagents for the preparation of DNA/RNA libraries for NGS.

Electrophoresis and Detection

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Analysis of a DNA sequence can be accomplished via a method called electrophoresis.

Electrophoresis is a term that basically describes the movement of molecules via an electric current and separation of those molecules based on size. You can skillfully perform electrophoresis and detect reliable data with Our wide array of Genomic life sciences tools and solutions from trusted brands.

See our entire agarose offering for your nucleic acid gel electrophoresis needs.

Choose from a variety of different blotting apparatus for Southern, Western, and Northern dot blotting procedures.

See our selection of blotting papers for blotting processes.

These electrophoresis buffers offer the ultimate in convenience.

Find the ethidium bromide format you need.

We offer all the electrophoresis stains for your needs.

View our wide selection of horizontal gel electrophoresis systems.

Choose from our selection of hybridization ovens with rapid heat-up capabilities and precise temperature control.

Molecular weight markers are ideal for verification of PCR products and for size analysis of digested DNA.

Systems delivering highly reproducible, quantitative data.

Select the power supply you need for your electrophoresis and blotting applications.

We offer a large variety of transilluminators to meet your needs.

Find the most popular UV crosslinkers.

DNA/RNA Modification, Cloning & Delivery

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Genetic modification differs from cloning. Cloning creates an exact copy of all or part of an organism's DNA, while genetic modification makes changes to existing DNA to create a new, modified version of the genome.

Find everything your lab needs for DNA/RNA modification, cloning and delivery. From DNases to transfection reagents, Avantor offers all the essential tools.

See our wide selection of kits for cloning and ligation.

We offer a large variety of competent cells for cloning and protein work

Enzymes and libraries for CRISPR/Cas9.

See our extensive range of enzymes capable of degrading DNA for multiple applications.

View all the best-in-class Electroporators we offer.

A full line of Electroporation Cuvettes to meet your needs.

Increase transformation and transposition efficiencies with a high-quality Electroporation Buffer from Avantor.

DNA and RNA ligases for cloning, mutagenesis and NGS.

Get the restriction enzymes you need – right here.

See our offer of RNase enzymes to cleave the RNA molecules.

See our wide offering of Transfection Reagents.

Genomic Life Sciences: An Overview
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Human genetics has many applications in medicine, biotechnology, anthropology and other social sciences.

Mapping a human genome (the complete set of genes or genetic material present in a cell or organism) is time-consuming and produces a terabyte (TB) of unorganized data.

As technology advances and that data becomes easier to store and comprehend, more healthcare providers will use it to diagnose and treat patients advancing personalized medicine.

Genomic life sciences uses a combination of DNA sequencing methods and bioinformatics to sequence, assemble and analyze the structure and function of genomes.

Genomics in the Lab
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Genomic life sciences utilize modern DNA technology to analyze the structure and function of a complete set of DNA within an organism.

This requires a variety of tools and techniques to be used in the lab:

  • Electrophoresis and purification systems to isolate DNA templates. ·
  • Polymerase Chain Reaction (PCR) and sequencing to determine the sequence and map of the DNA base code. ·
  • Microarrays and genotyping to determine the similarity and differences between sequences, mass spectrometry for analysis of oligonucleotides (short DNA or RNA molecules). ·
  • Next- generation sequencers to analyze whole genomes.

Most scientific laboratories will use some kind of genomic tool in their research, clinical or forensic applications.

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Ready to move your next innovation forward? We can help.

Contact us to speak with a member of our team.

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