"mRNA"
Innovative alternative to LNPs for mRNA therapeutics - In vivo-jetRNA®+
Supplier: Polyplus-transfection
In vivo-jetRNA®+ is a ready-to-use, efficient and stable lipid-based transfection reagent optimised for in vivo mRNA delivery.
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HA(FL)-H1N1 mRNA
Supplier: OZ BIOSCIENCES
HA(FL)-H1N1 mRNA has been designed to produce high expression level of the full length (HA) hemagglutinin surface glycoproteins.
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TriLink® CleanCap® M6 Cas9 ModTail™ mRNA (N1MePsU)
Supplier: TriLink BioTechnologies
This mRNA construct, produced via in vitro transcription (IVT), expresses a version of the Streptococcus pyogenes SF370 CRISPR Associated Protein 9 (Cas9) protein. Cas9 functions as part of the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform double-stranded DNA cleavage.
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TriLink® CleanCap® OVA mRNA (5 moU)
Supplier: TriLink BioTechnologies
Ovalbumin (OVA) is a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunisation and biochemical studies and is an established model allergen for airway hyper-responsiveness.
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mRNA transfection reagents, RmesFect™
Supplier: OZ BIOSCIENCES
RmesFect™ transfection reagent is based on the TEE-technology and is specifically designed for mRNA transfection with high efficiency and low toxicity. It is suitable for in vitro mRNA (dsRNA) transfection in a large variety of cells.
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TriLink® CleanCap® Beta gal mRNA (5moU)
Supplier: TriLink BioTechnologies
β-galactosidase (β-gal), a protein product of the bacterial LacZ gene, catalyzes the conversion of β-galactosides into monosaccharides. β-gal is a common marker gene used to assess transfection efficiency.
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Anti-SR-A1, Serine/Arginine-Rich pre-mRNA Splicing Factor Rabbit Polyclonal Antibody
Supplier: US Biological
Anti-SR-A1, Serine/Arginine-Rich pre-mRNA Splicing Factor Rabbit Polyclonal Antibody
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Molecular models: RNA, Molymod®
Supplier: SPIRING ENTERPRISES
The Molymod system is the original dual-scale system of high quality molecular models.
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MagicPrep™ NGS System
Supplier: Tecan
MagicPrep™ NGS system is a new category of automated laboratory equipment that provides push button simplicity for NGS library preparation. The Revelo DNA-Seq Enz for MagicPrep™ NGS library preparation kit provides all the reagents for generating DNA-Seq libraries on the MagicPrep™ NGS system.
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Accessories for 1-step human in vitro protein expression kit, Pierce™
Supplier: Thermo Fisher Scientific
Control tGFP mRNA, 10 µg (0,75 µg/µl in 0,1 mM EDTA)
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Anti-THOC2 Rabbit Polyclonal Antibody (Cy5.5®)
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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Anti-THOC2 Rabbit Polyclonal Antibody
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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Anti-THOC2 Rabbit Polyclonal Antibody (Cy5®)
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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Anti-THOC2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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Anti-THOC2 Rabbit Polyclonal Antibody (Cy7®)
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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Anti-THOC2 Rabbit Polyclonal Antibody (Cy3®)
Supplier: Bioss
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim.
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