"Stemcell Technologies"

Supplier: Stemcell Technologies

Serum- and BPE-free medium for human small airway epithelial cells cultured at the air-liquid interface.

Supplier: Stemcell Technologies

RANTES (regulated upon activation, normal T cell expressed and secreted), also known as CCL5, is a member of the CC family of chemokines and is able to recruit leukocytes to sites of inflammation (Schall et al.). RANTES is secreted by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells (Aldinucci and Colombatti; Soria and Ben-Baruch). This chemokine exerts its effect by interacting with the chemokine receptors CCR1, CCR3, CCR4, and CCR5. RANTES plays an active role in recruiting a variety of leukocytes into inflammatory sites, including T cells, macrophages, eosinophils, and basophils. In collaboration with certain cytokines that are released by T cells such as IL-2 and IFN-γ, RANTES also induces the activation and proliferation of NK cells to generate CC chemokine-activated killer cells, which are highly cytolytic (Lv et al.; Maghazachi et al.). It has been shown that RANTES produced by CD8+ T cells inhibits HIV infection of primary human peripheral blood mononuclear cells (Appay and Rowland-Jones; Cocchi et al.).

Supplier: Stemcell Technologies

Kit containing ClonaCell™-TCS medium and antibiotic G418.

Supplier: Stemcell Technologies

Cell dissociation reagent.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human CD56 (NCAM), PE­conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, PE-conjugated.

Supplier: Stemcell Technologies

Goat polyclonal antibody against mouse IgG (H+L).

Supplier: Stemcell Technologies

Hamster (Armenian) monoclonal IgG antibody against mouse CD11c, FITC-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD90 (Thy-1), PE-conjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD138 (syndecan-1), unconjugated.

Supplier: Stemcell Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee, horse CD38, biotin-conjugated.

Supplier: Stemcell Technologies

Hamster (Syrian) monoclonal antibody against mouse KLRG1, APC-conjugated.

Supplier: Stemcell Technologies

Conditional reprogramming medium for epithelial cell expansion.

Supplier: Stemcell Technologies

SARS-CoV-2 Recombinant Spike Protein, aa16-685 is expressed in HEK293 cells and is one of four structural proteins encoded by the SARS-CoV-2 genome. The Spike Protein plays a key role in attachment to host cells, allowing invasion through clathrin-mediated endocytosis. The Spike Protein can be cleaved by host cell proteases after aa685 to yield the N-terminal S1 subunit and C-terminal S2 region. The S1 subunit is responsible for interacting with the host cell receptor (angiotensin-converting enzyme II) through a receptor-binding domain that is highly conserved with SARS-CoV. The S1 subunit has two conformations: a ‘down’ conformation in which the receptor is inaccessible, and an ‘up’ conformation in which the receptor is accessible. These conformational changes are key for monoclonal antibody drugs and vaccine development. SARS-CoV-2 Recombinant Spike Protein contains a polyhistidine tag at the amino terminus; it also contains a FLAG tag at the carboxy terminus.

Supplier: Stemcell Technologies

Rat monoclonal IgG2b, antibody against mouse MHC Class II (I-A/I-E), unconjugated.

Supplier: Stemcell Technologies

Immunomagnetic negative selection kit.