"Alsto"

Supplier: Bioss

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Supplier: Rockland Immunochemicals

This product was also tested in a gel supershift assay and found to be reactive against RFX5 complexes using 0.5 to 1.0 µl per assay.  This product was also tested in a gel supershift assay and found to be reactive against RFX5 complexes.

Supplier: Bioss

NPW is a 165 amino acid secreted protein that is cleaved into two chains: neuropeptide W-23 (also designated NPW23 or L8) and neuropeptide W-30 (also known as NPW30 or L8C). Both NPW neuropeptides activate G-protein coupled receptors in the central nervous system to enhance cortisol secretion. Highly expressed in lymphoblastic leukemia, colorectal adenocarcinoma, fetal kidney, trachea and substantia nigra, NPW is also found at low levels in placenta, ovary, testis and uterus. NPW functions in organization of neuroendocrine signals and is also thought to enhance food and water intake as well as stress responses. The gene encoding NPW maps to human chromosome 16p13.3.

Supplier: Bioss

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Supplier: Abcam

Anticancer and antibiotic agent. Crosslinks DNA. Inhibits DNA synthesis and nuclear division. Also induces apoptosis.

Supplier: AAT Bioquest

Dihydrofluorescein diacetate (also called fluorescin diacetate) is hydrolyzed by cellular esterases to dihydrofluorescein (also called fluorescin) and is then oxidized to fluorescein primarily by H₂O₂.

Supplier: Merck

Sodium metabisulphite is primarily used as an antioxidant and antimicrobial agent in a wide variety of foods and drugs. It is also used as the main additive in the prevention of melanosis.

Supplier: Merck

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques. The CRM may also find the following uses:

Supplier: VWR Chemicals

Staining protein after electrophoretic separation. Also used to determine chloride ions in solution.

Supplier: Abcam

Competitive NMDA receptor glutamate site antagonist. Also available as the sodium salt.

Supplier: SWANN MORTON

Stainless steel. Originally developed for use with skin grafts, these blades are also suitable for a wide range of other applications.

Supplier: Simport Scientific

These disposable biopsy cassettes are designed to hold biopsy specimens during the embedding process. They are also designed as a storage file.

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: Bioss

Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).

Supplier: Apollo Scientific

Vismodegib is an inhibitor of hedgehog pathway with IC50 of 3 nM and also inhibits P-gp IC50 30 M.

Supplier: Bioss

The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.