Millicell cell culture insert plates are a patented device designed to support cell growth and differentiation of endothelial and epithelial cell lines, including CaCo-2.

• Isopore™ matrix
• 0,11 cm² filtration area
• Tissue Culture (TC)-treated surface binding type
• Dimension: 84,8×128×26,2 mm

Seed-and-feed systems
Automated liquid handling systems and span pipettes
Basolateral and apical access to cells
Transepithelial electrical resistance (TEER) measurement systems

The Millicell device is available with a 0,4 µm PCF and a variety of PET membrane pore sizes. The plate is designed for maximum user convenience and incorporates features such as apical assist for easier pipetting and basolateral access. To reduce the risk of monolayer contamination, the membrane plates have feet to elevate the plate above the work surface when disassembled from the feeder tray. Tear drop-shaped receiver wells eliminate air bubbles as plates are assembled.

They are optimised to grow and sustain high integrity cell monolayers. Cells grown on Millicell plate membranes grow better than on plastic because the cells are nourished from both the apical and basolateral sides. Cell growth and function more closely mimic in vivo. The plates are designed for analysis as well as cell growth and can be used manually or with automated cell seeding, feeding and washing systems.

With this complete system, you can grow, feed, and analyse cells in one membrane-bottom plate. The plate can be used with either a single-well or a multi-well feeding tray. At the time of transport analysis, the plate is simply transferred to a multi-well transport tray for analysis.