Maturation kit for generation of functional midbrain-type neurons from human ES and iPS cell-derived neuronal precursor cells.

The STEMdiff™ Midbrain Neuron Maturation Kit is used in conjunction with the STEMdiff™ Midbrain Neuron Differentiation Kit to generate a mixed population of midbrain-type neurons from neural progenitor cells derived from human pluripotent stem cells. These media will produce a population of midbrain neurons (≥ 15% TH-positive dopaminergic neurons; ≥ 90% class III βtubulin-positive neurons; < 10% GFAP-positive astrocytes). Cells derived using these products are versatile tools for modeling human neurological development and disease, drug screening, toxicity testing, and cell therapy validation.