- Antikroppstyp:Primär
- Antikroppsnamn:CD28 molecule
- Antigensymbol:CD28
- Klonalitet:Monoclonal
- Klon:CD28.2
- Konjugation:Unconjugated
- Flödescytometri:Yes
- Värd:Mouse
- ImmunKemi:Yes
- Immunutfällning:Yes
- Isotyp:IgG1 kappa
- Korsad adsorption:No
- Form:liquid
- Gen-ID:P10747
- Antigen synonymer:CD28
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Förvaringstemperatur:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Tested applications:Functional
- Rening:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Förp.:0,1 mg
The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction.
Type: Primary
Antigen: CD28
Clonality: Monoclonal
Clone: CD28.2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human