The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways.

• Stability: One year from date of shipment when stored at −20 °C
• Quality control: Tested by ESI-MS
• Purity: HPLC purified
• UniProt ID: O75688

This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Single siRNA duplex (10 nmol) can be ordered.

Number of transfections: Approximately 330 transfections/2 nmol in 24-well plate under optimized conditions (final conc. 10 nM).