Specifikationer
- Antikroppstyp:Primär
- Antikroppsnamn:BRWD3
- Klonalitet:Polyclonal
- Konjugation:Alexa Fluor® 680
- Värd:Rabbit
- ImmunKemi:Yes
- ImmunoFluorescens:Yes
- Isotyp:IgG
- Western blot:Yes
- Epitop:1701-1802/1802
- Form:Liquid
- Antigen synonymer:Bromo domain containing protein disrupted in leukemia|BRODL|Bromodomain and WD repeat domain containing 3|BRWD3_HUMAN|Novel WD repeat domain protein
- Modifiering:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molekylvikt:203 kDa
- Förvaringstemperatur:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human BRWD3
- Tested applications:ICC
- Rening:Purified by Protein A
- Förpackningstyp:Vial
- Förp.:100 µl
Specifikationer
Om denna produkt
Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterised by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.
Type: Primary
Antigen: BRWD3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 1701-1802/1802
Host: Rabbit
Isotype: IgG
Reactivity: