MagBeads Fast Circulating DNA Kit is intended for purification of high-quality circulating DNA (cfDNA) from cell-free body fluids (such as plasma, serum). The purified DNA is suitable for direct use in downstream applications such as PCR, real-time PCR, Biochip analysis and NGS.

• High quality DNA: intact, high yields and free from inhibitors
• High throughput: compatible with a wide range of automated nucleic acid purification platforms
• Flexibility: manual and automation mode of extraction
• Environmentally friendly: no phenol/chloroform or other toxic chemicals

MagBeads Fast Circulating DNA Kit is based on the purification method of high binding magnetic particles. The sample is lysed and digested. RNA is released into the lysate. After addition of magnetic particles and binding solution, RNA will be adsorbed on the surface of magnetic particles, and impurities such as proteins will be removed without adsorption.

The adsorbed particles were washed with washing buffer to remove the proteins and impurities, washed with ethanol to remove salts. Finally the RNA was eluted with elution buffer.