Deoxynivalenol-¹³C₁₅ (¹³C₁₅-DON) is a fusarium mycotoxin which belongs to trichothecene class of compounds.

¹³C₁₅-DON may be used as an internal standard for the identification of DON in maize by high performance liquid chromatography (HPLC) electrospray ionisation (ESI) mass spectrometry (MS/MS). Cereals and cereal-based compound animal feeds by LC-MS/MS operating on selected reaction monitoring (SRM) mode. Bioaerosols collected from Serpula lacrymans damaged homes by HPLC-MS/MS in multiple reaction monitoring (MRM) mode. It may also be used as an internal standard for the determination of HT-2 toxin, nivalenol and patulin in bioaerosols obtained from dairy cattle shed by HPLC-MS/MS.