Anti-MECP2 Mouse Monoclonal Antibody [clone: 4F11]
BSENM-1809-100
- Antikroppstyp:Primär
- Antikroppsnamn:Methyl-CpG binding protein 2 (MeCP2)
- Antigensymbol:MECP2
- Klonalitet:Monoclonal
- Klon:4F11
- Konjugation:Unconjugated
- Värd:Mouse
- ImmunKemi:Yes
- ImmunoFluorescens:Yes
- Isotyp:IgG1
- Reaktivitet:Human,Rat,Mouse
- Western blot:Yes
- Mått:Purified IgG
- Form:Lyophilized
- Antigen synonymer:MeCp2|MeCp-2 protein
- UniProtKB:Uniprot # P51608
- Förvaringstemperatur:Store lyophilised antibody at 2-8 °C. After reconstitution divide into aliquots and store at –20 °C for long-term storage. Store at 2-8 °C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
- Shipping temperature:Ambient
- Immunogen:Full-length recombinant human protein
- Rening:Affinity purified
- Storlek:100 µg
- Förp.:100 µG
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org
Western blotting (1:5,000-1:10,000) and Immunohistochemistry (1:1,000-1:5,000). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: MECP2
Clonality: Monoclonal
Clone: 4F11
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat