Matrix Metalloproteinase-12 (MMP-12) fluorometric drug discovery kit
ENZOBMLAK4030001
:
- Förp.:1 KIT
- Beskrivning:Matrix Metalloproteinase-12 (MMP-12) fluorometric drug discovery kit
- Seq:02
- Storage conditions:−80 °C
- Applikation:Colorimetric detection, HTS activity assay
- Storlek:1 kit
A QuantiZyme™ Assay System. The MMP-12 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-12 (MMP-12, metalloelastase, macrophage elastase) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH.
Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format.
: Kit contains MMP-12 Enzyme (human) (recombinant), Substrate, Calibration Standard, Prototypic Control Inhibitor (NNGH3), Assay Buffer, 96-well Microplate and a detailed instruction booklet.