Om denna produkt
Leukotrienes are metabolic products of arachidonic acid formed by the action of 5-lipoxygenase (5-LO), with the principal products being leukotrienes C4 (LTC4) and B4 (LTB4). Leukotriene B4 (LTB4) stimulates leukocyte functions including lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been implicated as a potent mediator of inflammatory diseases and immunoregulation. The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are formed by addition of cysteine derivatives to LTA4. The conversion of LTA4 to LTC4 by the enzyme LTC4 synthase limits the rate of cysteinyl leukotriene formation. Cysteinyl leukotrienes are potent lipid mediators in inflammation, inducing smooth muscle contractions and increased capillary permeability.
Type: Primary
Antigen: LTC4
Clonality: Monoclonal
Clone: 6E7
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human, Mouse, Rat
Specifikationer
- Catalog No:
- ENZOADI9059020200
- ENZOADI9059020050
- Antigensymbol:
- LTC4
- LTC4
- Antikroppsnamn:
- Leukotriene C4
- Leukotriene C4
- Antikroppstyp:
- Primär
- Primär
- Klonalitet:
- Monoclonal
- Monoclonal
- Konjugation:
- Unconjugated
- Unconjugated
- Klon:
- 6E7
- 6E7
- Reaktivitet:
- Human, Rat, Mouse
- Human, Rat, Mouse
- Värd:
- Mouse
- Mouse
- Isotyp:
- IgG
- IgG
- ELISA:
- Yes
- Yes
- Immunogen:
- Leukotriene C4
- Leukotriene C4
- Form:
- Liquid
- Liquid
- Rening:
- purified by Protein G affinity chromatography
- purified by Protein G affinity chromatography
- Storage buffer:
- PBS, pH 7,2, containing 50% glycerol and 0,09% sodium azide.
- PBS, pH 7,2, containing 50% glycerol and 0,09% sodium azide.
- Förvaringstemperatur:
- –20 °C
- –20 °C
- Shipping temperature:
- Shipped on blue ice
- Shipped on blue ice
- Tested applications:
- Radio Immunoassay
- Radio Immunoassay