- Förp.:50 µG
- Protein/peptide type:Recombinant
- Källa:E. coli
- Species:Human
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:HC11|Monocyte chemotactic and activating factor|MCAF|Monocyte secretory protein JE|Monocyte chemotactic protein 1|CCL2|Monocyte chemoattractant protein 1|Small-inducible cytokine A2|MCP-1|C-C motif chemokine 2
- Protein/peptide name:CCL2
- Renhet:> 95% as determined by reducing SDS-PAGE
- Molekylvikt:8.7 kD
- Sequence:Gln24-Thr99
- Formulering:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.
This recombinant protein can be used for biological assays. For research use only.