Anti-TMEM59L Rabbit Polyclonal Antibody
Katalog # PRSI6435
Leverantör: ProSci Inc.
Specifikationer
- Antikroppsnamn:Transmembrane Protein 59 Like
- Antigensymbol:TMEM59L
- Klonalitet:Polyclonal
- Konjugation:Unconjugated
- ELISA:Yes
- Värd:Rabbit
- ImmunKemi:Yes
- ImmunoFluorescens:Yes
- Isotyp:IgG
- Reaktivitet:Human,Rat,Mouse
- Western blot:Yes
- Antigen synonymer:BSMAP|C19orf4|Brain-specific membrane-anchored protein|Transmembrane protein 59-like|TMEM59L
- Storage buffer:PBS containing 0.02% sodium azide
- Immunogen:TMEM59L antibody was raised against a 19 amino acid synthetic peptide near carboxy terminus of human TMEM59L.
- Tested applications:E, WB, IHC, IF
- Rening:Affinity chromatography purified via peptide column
- Storlek:100 µg
- Förp.:100 µG
Specifikationer
Om denna produkt
TMEM59L Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
Type:
Antigen: TMEM59L
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat