Specifications
- Antikroppstyp:Primär
- Antikroppsnamn:SWI/SNF Related Matrix Associated Actin Dependent Regulator of Chromatin Subfamily D Member 3
- Antigensymbol:SMARCD3
- Klonalitet:Polyclonal
- Konjugation:Alexa Fluor® 647
- Värd:Rabbit
- ImmunKemi:Yes
- Isotyp:IgG
- Reaktivitet:Human,Rat,Mouse
- Korsad adsorption:No
- Form:liquid
- Gen-ID:6604
- Antigen synonymer:CRACD3|BAF60C|Rsc6p
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Förvaringstemperatur:Store at –20 °C for 12 months
- Koncentration:1 μg/μl
- Shipping temperature:4°C
- Rening:Purified by Protein A
- Förp.:100 µl
Specifications
About this item
SMARCD3, is a member of the SMARCD family and contains one SWIB domain. Two isoforms, isoform 1 and isoform 2 exist due to alternative splicing events. Both isoforms are expressed in placenta, salivary gland, kidney, brain, trachea, uterus, prostate, testis, thyroid, spleen and heart, while isoform 1 is also expressed in adipose tissue and skeletal muscle. Localizing to the nucleus, SMARCD3 is a component of the ATP-dependent chromatin remodeling complex SNF/SWI and is believed to play a role in nucleosome remodeling. SMARCD3 also plays an important role in the regulation of muscle development. In mice, the silencing of the gene en-coding SMARCD3 leads to defects in heart morphogenesis. In addition, both isoforms of SMARCD3 directly interact with and function as coactivators for several transcription factors.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: SMARCD3
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat