- Antikroppstyp:Primär
- Antikroppsnamn:ADP-Ribosylation Factor-Like 1
- Antigensymbol:ARL1
- Klonalitet:Polyclonal
- Konjugation:Alexa Fluor® 647
- Värd:Rabbit
- ImmunKemi:Yes
- Isotyp:IgG
- Reaktivitet:Human,Rat,Mouse
- Korsad adsorption:No
- Form:liquid
- Gen-ID:400
- Antigen synonymer:ADP-ribosylation factor-like protein 1|ARFL1
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Förvaringstemperatur:Store at 4°C for 12 months
- Koncentration:1 μg/μl
- Shipping temperature:4°C
- Rening:Purified by Protein A
- Förp.:100 µl
The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins (1–3). ARFs influence vesicle trafficking and signal transduction in eukaryotic cells (1–3). ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with golgi membranes and the association of actin to the golgi via rho family-dependent G-protein localization (Rac, CDC42) and WASP/Arp2/3 complexes (3–7). Additionally, ARFs play a central role in maintenance of organelle integrity, assembly of coat proteins, and activation of phospholipase D (5–7). The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6); members of each class share a common gene organization (8,9). The human ARF6 gene maps to chromosome 7q22.1, contains five exons and four introns, and encodes a 175 amino acid protein (8,9).
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: ARL1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat