Specifikationer
- Antikroppstyp:Primär
- Antikroppsnamn:Plasminogen Activator, Tissue
- Antigensymbol:PLAT
- Klonalitet:Polyclonal
- Värd:Rabbit
- Isotyp:IgG
- Reaktivitet:Human,Mouse
- Western blot:Yes
- Form:Lyophilized
- Gen-ID:5327
- Antigen synonymer:T-PA|TPA
- UniProtKB:P00750
- Förvaringstemperatur:At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
- Immunogen:E.coli-derived human TPA recombinant protein (Position: H366-P562). Human TPA shares 83% and 84% amino acid (aa) sequence identity with mouse and rat TPA, respectively.
- Rening:Immunogen affinity purified.
- Storlek:100 µg/vial
- Förp.:100 µG
Specifikationer
Om denna produkt
Rabbit IgG polyclonal antibody for Tissue-type plasminogen activator(PLAT) detection. Tested with WB in Human;Mouse.
PLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
WB: The detection limit for TPA is approximately 0.1ng/lane under reducing conditions.
Tested Species: In-house tested species with positive results.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Type: Primary
Antigen: PLCB1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat