The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB and CD45RO.
The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Type: Primary
Antigen: PTPRC (protein tyrosine phosphatase, receptor type, C)
Clonality: monoclonal
Clone: 30-F11
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b Kappa
Reactivity: Mouse
- Catalog No:
- 50-0451-U025
- 50-0451-U100
- Antigensymbol:
- PTPRC
- PTPRC
- Antikroppsnamn:
- Protein tyrosine phosphatase receptor type C
- Protein tyrosine phosphatase receptor type C
- Antigen synonymer:
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Antikroppstyp:
- Primär
- Primär
- Klonalitet:
- Monoclonal
- Monoclonal
- Konjugation:
- PE (Phycoerythrin)
- PE (Phycoerythrin)
- Klon:
- 30-F11
- 30-F11
- Reaktivitet:
- Mouse
- Mouse
- Värd:
- Rat
- Rat
- Gen-ID:
- 19264
- 19264
- Isotyp:
- IgG2b kappa
- IgG2b kappa
- Western blot:
- Yes
- Yes
- ImmunKemi:
- Yes
- Yes
- Immunutfällning:
- Yes
- Yes
- ImmunoFluorescens:
- Yes
- Yes
- Flödescytometri:
- Yes
- Yes
- Neutralisation:
- Yes
- Yes
- Korsad adsorption:
- none
- none
- Förvaringstemperatur:
- Cool
- Cool
- Shipping temperature:
- Ice
- Ice
- Tested applications:
- Flow Cytometry
- Flow Cytometry