Purvalanol A ≥99%
Supplier: ENZO LIFE SCIENCES
Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B.
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Purvalanol A
Supplier: Apollo Scientific
Free base. Purity>99%. Purvalanol A is a cell-permeable, potent, and selective cyclin-dependent kinase (CDK) inhibitor.
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Purvalanol A ≥98%, crystalline solid
Supplier: Cayman Chemical
Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.