"Solid Phase Extraction"

Supplier: VARIAN

The water-wettable, hydroxylated exterior allows excellent flow, even with biological fluids. A gradient of polarity on the polymer surface shunts small analytes to the more hydrophobic centre of the polymer bead, where they are retained prior to the washing and elution steps. Plexa provides these performance enhancements due to a unique polymeric architecture with a non-retentive, hydroxylated, amide-free surface and a non-polar PS/DVB core for retaining small molecules.

Supplier: VARIAN

PBA is a unique sorbent consisting of a phenylboronic acid covalently linked to a silica gel surface. Covalent processes result in a higher retention to the sorbent surface than other mechanisms, resulting in superior clean-up. The boronate group has a high specificity for cis-diol containing compounds such as catechols, nucleic acids, low molecular weight proteins and carbohydrates.

Supplier: VARIAN

Bond Elut™ PRS is a strong cation exchange sorbent that is also relatively high in polarity. With no appreciable degree of hydrophobicity, in non-polar solvents, PRS is capable of polar and hydrogen bonding interactions. Due to the very low pKa of PRS, a high ionic strength eluent must be used, and so the use of PRS is recommended for weaker cationic species such as pyridinium compounds.

Supplier: VARIAN

Bond Elut™ NH₂ is a weaker anion exchanger than sorbents such as SAX (a quaternary amine sorbent that is always charged) and is therefore a better choice for retention of very strong anions, such as sulfonic acids, which may retain irreversibly on a SAX sorbent. Similar to Diol and SI sorbents, Bond Elut™ NH₂ is excellent for the separation of structural isomers.

Supplier: Whatman products (Cytiva)

The 10 ml UNIFILTER is used with large sample or reagent volumes. Typical applications include biomolecule purification by solid phase extraction and organic synthesis in combinatorial chemistry library generation.

Supplier: VARIAN

Bond Elut™ Diol (2OH) resembles unbonded silica in its tendency for strong hydrogen bonding with analytes. 2OH can also be employed in the non-polar mode because the hydrocarbon spacer on its functional group provides enough non-polar character for retention of hydrophobic analytes. Bond Elut™ Diol is a listed SPE device for the DIN 14333-1 method on benzimidazole fungicides.

Supplier: VARIAN

Bond Elut™ DEA bears some resemblance to Bond Elut™ NH₂ in its properties but with a slightly lower capacity as an anion exchange sorbent. DEA has a moderately non-polar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C₈ but less polar than C₂ or CN-E.

Supplier: VARIAN

Bond Elut™ C8 is very similar in properties to C18, but is not as retentive for non-polar compounds, due to its shorter hydrocarbon chain, and therefore reduced carbon loading. C8 is an excellent replacement for C18 when analytes are too strongly retained for effective elution. The potential for polar interactions is somewhat higher than for C18 because there is less coverage of the silica surface. These polar interactions are not, however, a significant property of C8.

Supplier: VARIAN

Clean PP reservoirs contain two PP frits pre-inserted, an ideal configuration for simple filtration.

Supplier: Thermo Fisher Scientific

Solid Phase Micro Extraction (SPME) uses a thin-fused silica fiber coated with a sorbent which enables extraction of compounds of interest from liquid or gaseous samples through absorption or adsorption. The fiber is then moved to the injector and the compounds thermally desorbed. The SPME consumables come in two formats SPME fibers and SPME arrows.

Supplier: VARIAN

Bond Elut™ PSA is an alkylated amine sorbent that contains two different amino functionalities, one secondary and one primary. This gives a slightly higher pKa and ionic capacity compared to Bond Elut™ NH₂. The PSA functional group is a very effective bidentate ligand and is therefore an excellent sorbent for chelation applications. PSA has a significantly higher carbon load than most amino functional sorbents and thus is a better choice for polar compounds, which retain too strongly on Bond Elut™ NH₂.

Supplier: MACHEREY-NAGEL

State-of-the-art spherical polymer for highest demands in solid phase extraction. PS/DVB copolymer with secondary and tertiary ammonium modification for mixed-mode SPE with weak anion exchange and reversed-phase properties (WAX).

Supplier: MACHEREY-NAGEL

CHROMABOND®, PE frits for PP columns, 6 ml

Supplier: VARIAN

Bond Elut™ C18 is the most hydrophobic, bonded silica sorbent in the Bond Elut™ range. It is the most popular SPE sorbent because of its extremely retentive nature for non-polar compounds. C18 is generally regarded as having the broadest spectrum of retention among bonded silica sorbents, since it retains most organic analytes from aqueous matrices. When analysing small to intermediate molecules, Bond Elut™ C18 can be used for desalting aqueous matrices prior to ion exchange, as salts pass through the sorbent unretained.

Supplier: VARIAN

Bond Elut™ SCX is a strong cation exchanger with a very low pKa. Although the pKa is similar to Bond Elut™ PRS, the presence of the benzene ring in the functional group increases the potential for non-polar interactions. This non-polar characteristic becomes particularly important when conducting ion-exchange from aqueous systems, where selectivity towards compounds exhibiting cationic and non-polar character is seen.

Supplier: VARIAN

Bond Elut™ NEXUS is an ultra-clean polymeric sorbent which has bi-modal porosity and a high surface area. NEXUS offers a nonpolar retention mechanism with no pre-conditioning required. The large particle size makes NEXUS ideal for extractions from highly viscous samples, such as horse urine.

Based on the same base polymer technology, Bond Elut™ NEXUS WCX is a weak cation exchange sorbent that offers extra selectivity for analytes, such as quaternary ammonium drugs and anabolic steroids.