2465 Results for: "STEMCELL Technologies"

Supplier: STEMCELL Technologies

Dilution buffer for matrix proteins.

Supplier: STEMCELL Technologies

Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen and Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma et al.). The majority of IL-2 is secreted by activated CD4+ and CD8+ T cells, although B cells and dendritic cells were found to produce IL-2 in small amounts. IL-2 downregulates immune responses to prevent autoimmunity during thymic development, influences the development of CD4+CD25+ regulatory T cells, and affects development of follicular helper T cells. IL-2 also controls inflammation by inhibiting Th17 differentiation (Banchereau et al.). High IL-2 levels in serum are associated with progression of scleroderma, rheumatoid arthritis, and gastric and non-small cell lung cancer, though no known disease can be directly attributed to the lack or excess of IL-2 (Gaffen and Liu).

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse B cells

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse T cells

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse naïve CD8+ T cells

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human CD34, Alexa Fluor® 488-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a, kappa isotype control antibody, APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2b antibody against human, rhesus, cynomolgus CD20, FITC-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse CD45, biotin-conjugated.

Supplier: STEMCELL Technologies

Rat monoclonal IgG2b antibody against mouse EPCR (CD201), FITC­conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG2a antibody against human, rhesus, cynomolgus CD184 (CXCR4), APC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against dextran, FITC-conjugated.

Supplier: STEMCELL Technologies

Immunodensity isolation of untouched B cells.

Supplier: STEMCELL Technologies

Immunomagnetic isolation of untouched mouse pan-dendritic cells (DCs)

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human CD56 (NCAM), FITC­conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, sooty mangabey CD123 (IL-3Rα), PerCP-Cy5.5-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD16, FITC-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human SSEA-5, PE-conjugated.

Supplier: STEMCELL Technologies

Mouse monoclonal IgM antibody against human, rhesus, rabbit TRA­1­60 (podocalyxin), unconjugated.

Supplier: STEMCELL Technologies

Serum- and BPE-free medium for expansion of primary human airway epithelial cells.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of mouse CD11c+ cells (e.g. dendritic cells (DC)) from mouse splenocytes or other tissues

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, chimpanzee, gibbon TRA-2-49 (tissue non-specific alkaline phosphatase), unconjugated.

Supplier: STEMCELL Technologies

Immunomagnetic positive selection of particle-free human cells labeled with APC-conjugated antibodies.

Supplier: STEMCELL Technologies

Mouse monoclonal IgG1 antibody against human, mouse CD105 (endoglin).

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human CD4+ cells for HLA analysis.

Supplier: STEMCELL Technologies

Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Yang et al.; Dorssers et al.; Broughton et al.). IL-3 is produced by activated T cells and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by basophils and eosinophils (Broughton et al.). The IL-3 receptor consists of a unique alpha subunit (CD123) and a beta common subunit (βc or CD131) that is shared with the receptors for IL-5 and GM-CSF, and is the principal signal transduction subunit for these cytokines. IL-3 binding to the heterodimeric receptor activates JAK/STAT, MAPK, and PI3K signaling pathways (Woodcock et al.). This product is animal component-free.

Supplier: STEMCELL Technologies

Column-free immunomagnetic positive selection of human CD33+ and CD66b+ cells for HLA analysis.

Supplier: STEMCELL Technologies

EasySep™ Red blood cell lysis buffer is for use as directed with EasySep™ or RoboSep™ whole blood kits for the lysis of red blood cells prior to separation from whole blood.

Supplier: STEMCELL Technologies

Single flow meter is specially designed to control the gas flow in hypoxia incubator chamber to generate a hypoxic environment for tissue culture.

Supplier: STEMCELL Technologies

Supplement for serum-free cell culture media.