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Manganese(II) sulphate monohydrate, pale pink powder

Supplier: MP Biomedicals

Magnesium sulphate is used as a colorant in dyes and red glazes for porcelain. As a trace essential element it is a nutritional factor for all animals; often a supplement in feed. It is used in biological assays to study the effects of manganese on the central nervous system, and to assess exposure limits.

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D-(+)-Maltose monohydrate ~99%, white powder

Supplier: MP Biomedicals

D-(+)-Maltose monohydrate is a component of starch and glycogen. It is a sugar composed of 2 α-D-glucose molecules coupled by an α(1→4) glycosidic bond. It is a reducing sugar with one anomeric carbon not linked in an anomeric bond. It contains a hemiacetal function and can mutarotate. Maltose is one product generated from starch and glycogen by the action of α-amylase.

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D-(+)-Trehalose dihydrate ≥99%, white powder cell culture reagent

Supplier: MP Biomedicals

Trehalose Dihydrate is an osmolyte, a chemical chaperone. It contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. It include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.

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Detergents, powder, rea-pur®

Detergents, powder, rea-pur®

Supplier: HIRSCHMANN

Surface cleaner that rapidly cleans materials such as glass, porcelain, rubber, plastics and metals of oil, grease, wax, resin, silicone, blood, protein and serum residues. Also suitable for cleaning and decontamination of walls and floors. Environmentally friendly as the active agents are biologically degradable.

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Mortar grinder, RM 200

Mortar grinder, RM 200

Supplier: Retsch GmbH

The mortar grinder RM 200 comminutes inorganic and organic substances to analytical fineness. It can mix and homogenise powders, suspensions and pastes. The grinder is also ideal for the uniform trituration of homeopathic and pharmaceutical products. Depending on the sample, amounts from approx. 10 to 190 ml can be processed in the RM 200.

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L(+)-Glutamic acid ≥99%, white powder

Supplier: MP Biomedicals

Glutamate is a key compound in cellular metabolism. It is the most abundant excitatory neurotransmitter in the vertebrate nervous system. It also serves as the precursor for the synthesis of the inhibitory GABA in GABA-ergic neurons. This reaction is catalyzed by glutamate decarboxylase (GAD), which is most abundant in the cerebellum and pancreas.

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Coomassie brilliant blue G-250, dark reddish purple powder C.I. 42655

Supplier: MP Biomedicals

Coomassie Brilliant Blue G-250 is a protein stain in electrophoresis. Brilliant Blue G has been used in the Bradford dye-binding protein assay.

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Potassium dihydrogen phosphate, anhydrous, white crystalline powder cell culture reagent

Supplier: MP Biomedicals

Storage: Room Temperature, desiccate
Potassium phosphate is a reagent with high buffering capacity. It occurs in several forms: monobasic, dibasic and tribasic (K3PO4). Most pH neutral potassium phosphate buffer solutions consist of mixtures of the monobasic and dibasic forms to varying degrees, depending on the desired pH.
Potassium phosphate monobasic is typically used as a component for a wide variety of media used in the culture of microorganisms. It is widely used in molecular biology, biochemistry, and chromatography. It is a component in phosphate buffered saline (PBS). In addition to helping maintain pH, it supplies essential phosphate.

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Light green SF yellowish, purple powder C.I. 42095

Supplier: MP Biomedicals

Acid Green 5 is useful as a general plasma stain, as a histological stain, and a cytological counterstain. Can be use as a cytological counterstain and as a substitute for aniline blue in Gomori′s one-step trichrome procedure.

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Sulphamethazine sodium salt, white powder

Supplier: MP Biomedicals

Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.

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Padlock control centres

Padlock control centres

Supplier: Brady

These padlock control centres provide safe storage and controlled access to padlocks.

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Dulbecco's phosphate buffered saline (DPBS), for cell culture, powder format, HyClone™

Dulbecco's phosphate buffered saline (DPBS), for cell culture, powder format, HyClone™

Supplier: HyClone products (Cytiva)

Balanced salt solution used for multiple cell culture applications (powder form).

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(-)-Quinine hydrochloride dihydrate, white powder

Supplier: MP Biomedicals

Quinine Hydrochloride is an alkaloid originally isolated from the Cinchona family of South American trees. It is an antimalarial agent, anticholinergic, antihypertensive and hypoglycemic agent.

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Bromophenol blue sodium salt, dark green powder ACS

Supplier: MP Biomedicals

Bromophenol blue is a tracking dye for alkaline and neutral buffer systems. It is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) gel electrophoresis.

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Coomassie® brilliant blue R-250, dark powder for electrophoresis

Supplier: MP Biomedicals

Coomassie® Brilliant Blue R-250 is a fast acting, sensitive dye, which can be used on SDS gels, IEF gels, and standard gels.

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Coomassie brilliant blue G-250, dark reddish purple powder for electrophoresis C.I. 42655

Supplier: MP Biomedicals

Brilliant blue G is a useful dye for SDS gels as it readily stains proteins with minimal background color. Protein bands can be visualised during staining. It has been used in the Bradford dye-binding protein assay.

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Folic acid ≥95%, orange powder cell culture reagent

Supplier: MP Biomedicals

Storage: Store at Room Temperature (15-30 °C). Protect from light.
Folic acid, also known as folate, is a B vitamin that can be found in a variety of fruits and vegetables. It can also be chemically synthesized. Folate, a watersoluble vitamin, helps the body form red blood cells and aids in the formation of genetic material within every body cell. Folic Acid is a hematopoietic vitamin present, free or combined with one or more additional molecules of L- (+)-glutamic acid, in liver, kidney, mushrooms, spinach, yeast, green leaves, and grasses.
A nutritional delivery form of folate. Folic acid and its derivatives are essential mediators of one-carbon metabolism within cells.

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Coomassie® brilliant blue R-250, purple powder C.I. 42660

Supplier: MP Biomedicals

Coomassie Blue R-250 is a triphenylmethane dye used extensively in SDS-PAGE for the analysis of proteins.

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PIPES ≥99%, white powder for molecular biology

Supplier: MP Biomedicals

PIPES is a zwitterionic N-substituted aminosulfonic acid "Good" buffer.
PIPES is used to buffer glutaraldehyde fixative solutions when fixing plant and/or animal tissue samples. This will help prevent the loss of lipids. It is also used to buffer glutaraldehyde and formaldehyde when fixing fungal zoospores for fluorescence microscopy and electron microscopy. PIPES tends to give optimal results.
Buffers can be made by adding a solution of base to PIPES free acid, titrating to the appropriate pH.

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Agarose, white powder, high resolution for molecular biology

Supplier: MP Biomedicals

Agarose High Resolution is an intermediate melting agarose with approximately twice the resolution capability of routine agarose. It is a purified linear galactan hydrocolloid isolated from agar or agar-bearing marine algae. It is ideal for the resolution of small DNA fragments in the range 20 bp to 2000 bp.
Agarose high resolution is an intermediate melting and gelling point agarose which exhibits superior sieving characteristics. It is recommended for analytical gels of DNA fragments under 1000 bp and is ideal for small DNA fragments down to 20 bp can be separated on 6 % gels. It resolves fragments differing in size by only 2 bp. Its use avoids the need for PAGE Southern and Northern transfers can be achieved efficiently from them at concentrations up to 2%. DNA fragments can be purified with high efficiency from this agarose gels up to 4% by using either a purification kit or an electroelution system.

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Stand bases, tripod

Stand bases, tripod

Supplier: USBECK Laborgeräte

Powder-coated steel, thickness 10 mm.

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Sodium chloride ≥99.5%, white crystalline powder for molecular biology

Supplier: MP Biomedicals

Sodium chloride is a commonly used chemical which is found widely in nature. It is considered to be an essential nutrient. Excess amounts of sodium chloride can destroy electrolyte balance and cause death in most animals, including humans.
Sodium chloride is used in a wide variety of biochemical applications, including intravenous fluids (normal saline is 0.9% w/v in water 10), density gradients 3,6, a diluent to increase ionic strength in buffers or culture media and in salt-out procedures in the isolation of DNA. It has also been used in high concentrations for preservation of foods since bacteria cannot grow in high salt conditions. A salt-ice mixture in the ratio of approximately 33 g sodium chloride to 100 g ice (at -1°C) will drop in temperature to as low as -21°C, depending on the rate of stirring and the size of the ice chunks.

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Sodium dodecyl sulphate (SDS) ≥99%, fine white powder, Ultrapure

Supplier: MP Biomedicals

SDS is an anionic detergent and wetting agent that is effective in both acid and alkaline solutions.
Used to solubilize and denature proteins for denaturing-PAGE. Most proteins bind SDS in a ratio of 1.4 g SDS per gram of protein. The charges intrinsic to the protein become insignificant compared to the overall negative charge provided by the bound SDS. The charge to mass ratio is essentially the same for each protein and will migrate in the gel based only on their size.

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L(+)-Asparagine, anhydrous ≥99%, white powder cell culture reagent

Supplier: MP Biomedicals

Storage: Store at Room Temperature (15-30 °C). Store Desiccated.
L-Asparagine is used in cell culture media and is a component of MEM non-essential amino acids solution. L-Asparagine has been shown to enhance ornithine decarboxylase activity in cultured human colon adenocarcinoma Caco-2 cells and in cultured IEC-6 intestinal epithelial cells. Spore germination in Bacillus subtilis has been increased in the presence of L-asparagine. An isoxazoline RGD mimic platelet GPIIb/IIIa antagonist has been prepared by chiral synthesis with L-asparagine as a starting material. L-Asparagine has been utilized in the synthesis of 4-azalysine building blocks for application to combinatorial chemistry.

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L(+)-Glutamine ≥99%, white powder cell culture reagent

Supplier: MP Biomedicals

Storage: Store at Room Temperature (15-30 °C)
L-Glutamine, the uncharged and amidated analog of L-glutamic acid, is an important amino acid for the incorporation of NH4+ into biomolecules. It is biosynthesized from NH4.
L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture.
L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

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Coenzyme A trilithium salt dihydrate ≥96%, white crystalline powder

Supplier: MP Biomedicals

Coenzyme A is an essential cofactor in enzymatic acetyl transfer reactions. The principal biologically active forms of pantothenic acid are coenzyme A (CoA) and acyl carrier protein (ACP). In CoA, the business center of the molecule is the pantothenic acid metabolite 4'-phosphopantetheine. Coenzyme A is comprised of 4'-phosphopantetheine linked by an anhydride bond to the nucloetide adenosine 5'-monophosphate. 4'-Phosphopantetheine itself is comprised of pantothenic acid linked at one end, via an amide bond, to beta-mercaptoethylamine, derived from L-cysteine, and at the other end to a phosphate group. The sulfhydryl group of 4'-phosphopantetheine, which is the business end of the coenzyme, forms thioesters with acyl groups producing acyl-CoA derivatives, including acetyl-CoA.
Coenzyme A facilitates removal of lipid peroxides by increasing mobilization of fatty acids, and promote repair of plasma membranes by activating phospholipid synthesis.

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Guanidinium hydrochloride ≥99%, white crystalline powder, Ultrapure

Guanidinium hydrochloride ≥99%, white crystalline powder, Ultrapure

Supplier: MP Biomedicals

Guanidine Hydrochloride is a protein denaturant and thus having an important role in molecular weight determinations.
Guanidine Hydrochloride is a strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine HCl is used in the isolation of RNA to dissociate the nucleoprotein into its nucleic acid and protein moieties. It is an inhibitor of RNase. Highly concentrated (6 - 8 M) Guanidine HCl solutions are used to denature native globular proteins. It apparently disrupts hydrogen bonds which hold the protein in its unique structure. However, there also is evidence suggesting that guanidine hydrocholoride may disrupt hydrophobic interactions by promoting the solubility of hydrophobic residues in aqueous solutions.

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Disposable powder samplers, SteriWare®

Disposable powder samplers, SteriWare®

Supplier: Sampling Systems

Designed to collect single large volume sample from a single known point of free flowing powders from drums, kegs, and most containers.

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Disodium hydrogen phosphate heptahydrate ≥98%, white crystalline powder ACS

Supplier: MP Biomedicals

Sodium phosphate dibasic heptahydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers.

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Sodium deoxycholate, white powder

Supplier: MP Biomedicals

Deoxycholic Acid Sodium Salt Monohydrate is an anionic biological detergent for the solubilization of membrane-bound proteins.

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