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5270 results for "ENZO LIFE SCIENCES"

5270 Results for: "ENZO LIFE SCIENCES"

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SB203580 ≥97%

Supplier: ENZO LIFE SCIENCES

Protein kinase inhibitor

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Water endotoxin-free, double distilled

Supplier: ENZO LIFE SCIENCES

Sterile, double distilled endotoxin-free water for use with TLRgrade™ or endotoxin-free grade reagents.

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Anti-HSP70 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

The 70 kDa heat shock protein Hsp70 belongs to the Hsp70 family of highly-related protein isoforms ranging in size from 66 kDa to 78 kDa. Hsc70 shares close biochemical and biological ties to Hsp70, and also belongs to the Hsp70 family. These proteins include cognate members found within major intracellular compartments and highly inducible isoforms predominantly cytoplasmic or nuclear in distribution. Members of the Hsp70 family function as molecular chaperones involved in such cellular functions as protein folding, transport, maturation and degradation, operating in an ATP-dependent manner. The molecular chaperones of the Hsp70 family recognize and bind to nascent polypeptide chains or partially folded intermediates of proteins, preventing their aggregation and misfolding, and the binding of ATP triggers a critical conformational change leading to the release of the bound substrate protein. Data demonstrates that with a ubiquitin-like domain at its amino terminus and its association with the 26S proteosome in HeLa cells, Bag-1 modulates the chaperone activity of Hsc70 and Hsp70. These findings reveal Bag-1's role as a physical link between the Hsc70/Hsp70 chaperone system and the proteasome. Experimental data also shows that the ATPase domain and the substrate-binding domain of Hsp70 (or Hsc70) cooperate to form a co-chaperone-chaperone complex with the synaptic vesicle cysteine string protein (csp), essential for normal neurotransmitter release.

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Corning Life Sciences

Why Choose Corning Fetal Bovine Serum?

Our vertically integrated FBS serum supply chain, from collection to scientist, allows us to provide a consistent supply of FBS.

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Anti-E6AP Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

Host: Mouse, Isotype: IgG1

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Rosiglitazone ≥97% (by HPLC)

Rosiglitazone ≥97% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Insulin sensitising agent.

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LH ELISA kit, grow cells

Supplier: ENZO LIFE SCIENCES

Highly sensitive LH ELISA kit enabling detection of LH in serum, plasma and tissue culture media in just 2 hours.

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Anti-ACTA2 Mouse Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

Host: Mouse, Isotype: IgG2b

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Chk 1 & 2 substrate

Supplier: ENZO LIFE SCIENCES

This peptide sequence, KKKVSRSGLYRSPSMPENLNRPR, corresponds to amino acids 206 to 225 of the phosphatase CDC25C, which is a phosphorylation target of Chk1 on Ser216.

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Coelenterazine ≥90% (by HPLC)

Coelenterazine ≥90% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Calcium dye.

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Anti-ACE Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

ACE1 (angiotensin converting enzyme-1, ACE) is a key regulator of blood pressure.

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trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride ≥98% (by UHPLC)

Supplier: ENZO LIFE SCIENCES

Inhibits ergosterol biosynthesis at the level of squalene epoxidase. Potent non-competitive inhibitor of squalene epoxidase from Candida (Ki=30 nM), inhibiting mammalian enzymes at higher concentrations (4-77 µM). It inhibits HUVEC proliferation and angiogenesis and displays interesting anti-inflammatory and free radical scavenging activities. Clinically useful antifungal agent.

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Bovine native Calmodulin (from Brain), Biotin

Supplier: ENZO LIFE SCIENCES

Isolated from bovine brain.

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3-Aminobenzamide

Supplier: ENZO LIFE SCIENCES

3-Aminobenzamide

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Matrix Metalloproteinase-7 (MMP-7) fluorometric drug discovery kit

Supplier: ENZO LIFE SCIENCES

A QuantiZyme™ Assay System. The MMP-7 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-7 (MMP-7, matrilysin) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.

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GW-9662 ≥98% (by HPLC)

Supplier: ENZO LIFE SCIENCES

PPAR ligand.

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Anti-Agrin Mouse Monoclonal Antibody [clone: Agr-33]

Supplier: ENZO LIFE SCIENCES

Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins at the neuromuscular junction during development.

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bpV(HOpic) ≥90% (by 51V-NMR)

Supplier: ENZO LIFE SCIENCES

PTP inhibitor, PTEN Inhibitor

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Methoprene acid ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Retinoid X receptor ligand.

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Anti-BIMS/EL/L Rat Monoclonal Antibody

Supplier: ENZO LIFE SCIENCES

Host: Rat, Isotype: IgG2a

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PDKtide, biotin

Supplier: ENZO LIFE SCIENCES

Protein kinase substrate

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Ponasterone A ≥95% (by HPLC)

Ponasterone A ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Ecdysteroid.

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Anti-8-ISO-PGF2 alpha Rabbit Polyclonal Antibody

Supplier: ENZO LIFE SCIENCES

Prostaglandin F2alpha (PGF2alpha) is formed in a variety of cells from PGH2, which itself is synthesized from arachidonic acid by the enzyme prostaglandin synthetase. PGF2alpha is often viewed as an antagonist to PGE2 due to their opposing effects on various tissues. PGF2alpha is a potent bronchoconstrictor and has been implicated in asthma attacks. PGF2alpha is also involved in reproductive functions including corpus luteum regulation, uterine contractions, and sperm motility. This has led to its use in terminating pregnancies and inducing labor at term. High levels of PGF2alpha have also been associated with preeclampsia.

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Human Recombinant 14-3-3theta/tau (from E. coli), HIS Tag

Supplier: ENZO LIFE SCIENCES

Produced in E. coli. Human 14-3-3τ/θ is fused at the C-terminus to a His-tag.

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Niltubacin

Supplier: ENZO LIFE SCIENCES

HDAC inhibitor

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BX-795 ≥97% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Inhibitor of PDK1, TBK1, IKK-ε, IRF3

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(-)-Arctiin (from Arctium lappa) ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Lignan derivative with antitumor activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic activity and is an antagonist for platelet activating factor and Ca²⁺.

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2',5'-Dideoxyadenosine ≥98% (by TLC)

Supplier: ENZO LIFE SCIENCES

Adenylate cyclase inhibitor

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Human recombinant HSP70 (from E. coli)

Supplier: ENZO LIFE SCIENCES

Produced in E.coli.

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2-(4-Isobutylphenyl)propanoic acid ≥99%

Supplier: ENZO LIFE SCIENCES

COX inhibitor

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