Supplier: Cayman Chemical

A number of tumor cells and cell lines have been observed to have highly upregulated expression and activity of fatty acid synthase (FAS). Inhibition of FAS by the irreversible inhibitor cerulenin leads to cytotoxicity and apoptosis in human cancer cell lines, an effect believed to be mediated by the accumulation of malonyl-coenzyme A in cells with an upregulated FAS pathway. Cerulenin also leads to profound weight loss and feeding inhibition in both high-fat diet wild type obese and leptin-deficient ob/ob mice.

Supplier: Cayman Chemical

DepNA (decanoyl-p-nitroaniline)

Supplier: Cayman Chemical

Anti-15-Hydroxy-PGDH Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-TRAIL-R4 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-Vtg Mouse Monoclonal Antibody [clone: ND-5C9]

Supplier: Cayman Chemical

Tin(II) chloride dihydrate

Supplier: Cayman Chemical

Cysteinyl Leukotriene Express is a competitive assay used for quantification of CysLT in urine, culture media, and other sample matrices.

Supplier: Cayman Chemical

N-Nervonoyl taurine

Supplier: Cayman Chemical

Estrone

Supplier: Cayman Chemical

Anti-CB1 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-Vtg Rabbit Polyclonal Antibody [clone: AA-1]

Supplier: Cayman Chemical

Anti-CD36 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: JC63.1]

Supplier: Cayman Chemical

Fumonisin B₁ is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)

Supplier: Cayman Chemical

Anti-GPR35 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-BLT1 Mouse Monoclonal Antibody [clone: 7B1]

Supplier: Cayman Chemical

Anti-COX-2 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.

Supplier: Cayman Chemical

iFSP1 is an inhibitor of apoptosis inducing factor mitochondria-associated 2/ferroptosis suppressor protein 1 (AIFM2/FSP1)

Supplier: Cayman Chemical

Human recombinant STING R224 variant (from E. coli)

Supplier: Cayman Chemical

Interferon regulatory factor 3 (IRF3) is a member of the IRF family that plays a crucial role in activation of innate immunity and inflammation in response to viral infection, functioning as a molecular switch for antiviral activity. Double-stranded RNA generated during a viral infection leads to IRF3 activation through serine/threonine phosphorylation by TBK1 (Item No. 22817) or IKKε (IKBKE) kinases, which induces a conformational change leading to its dimerization, nuclear localization, and association with CREB binding protein (CREBBP)/p300. The complex formed by this association, known as DRAF1, activates transcription of interferon α (IFN-α) and IFN-β as well as other IFN-induced genes, which play a critical role in the type 1 IFN-dependent immune response. Cayman’s IRF3 Polyclonal Antibody can be used for Western blot and ELISA applications. The antibody recognizes IRF3 at ~47 kDa from human samples.

Supplier: Cayman Chemical

BSA-Oleate monounsaturated fatty acid complex is composed of oleic acid and bovine serum albumin (BSA) at an approximately 6:1 molar ratio of oleate:BSA. It has been used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies.

Supplier: Cayman Chemical

Tyrosol is a phenol that has been found in olives and olive oil and has diverse biological activities.

Supplier: Cayman Chemical

For the determination of total calcium concentration in a variety of biological samples, as well as tissue homogenates and cell lysates.

Supplier: Cayman Chemical

BMS 345541 (trifluoroacetate salt) ≥98%

Supplier: Cayman Chemical

HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity.

Supplier: Cayman Chemical

BMS 195614 is a neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5 nM). It antagonizes agonist-induced coactivator recruitment and moderately decreases SMRT binding to RAR but does not significantly affect nuclear receptor corepressor binding.

Supplier: Cayman Chemical

For the quantification of PGIM in urine and other sample matrices.

Supplier: Cayman Chemical

Echinocandin B inhibits 1,3-β glucan synthase; inhibits incorporation of radiolabeled glucose into alkali-insoluble glucan by S. cerevisiae spheroplasts; inhibits growth of C. albicans in vitro (MIC = 3.9 µg/ml after 2 days)

Supplier: Cayman Chemical

Anti-CD36 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Potassium phosphate buffer solution (0,5 mol/l), pH value: 9,0