Stimulating T cells with HPV16 (L1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (L1) Peptide pool is a lyophilised mixture of 124 peptides from major capsid protein L1 of human papillomavirus type 16 (HPV16) consisting of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 505 on L1. L1 enters the nuclei of host cells via a Kap α2β1-mediated pathway (Nelson et al.). It cooperates with E2, another viral protein, to enhance viral DNA replication (Siddiqa et al.). L1 pentamers can assemble into virus-like particles (Chen et al. 2000; Chen et al. 2001). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.