- Antibody type:Primary
- Antigen name:GK2/Glycerol kinase 2
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat
- Western blot:Yes
- Epitope:101-200/553
- Form:Liquid
- Gene ID:2712
- Antigen synonyms:GLPK2_HUMAN|ATP:glycerol 3 phosphotransferase|Glycerokinase|GKP2|GK|GK 2|Glycerol kinase 2|GKTA|Glycerol kinase testis specic 2|EC 2.7.1.30
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
- Molecular weight:61 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human GK2/Glycerol kinase 2
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Type: Primary
Antigen: GK2/Glycerol kinase 2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 101-200/553
Host: Rabbit
Isotype: IgG
Reactivity: Human; Rat