Anti-Cyclin E1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)
BOSSBS-8929R-A680
: Bioss
- Antibody type:Primary
- Antigen name:Cyclin E1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human
- Western blot:Yes
- Epitope:251-350/410
- Form:Liquid
- Gene ID:898
- Antigen synonyms:CyclinE|CCNE1|CCNE 1|CCNE1_HUMAN|G1/S specic cyclin E|Cyclin Et|CCNE|Cyclin E1 antibody Cyclin Es
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Storage temperature:Store at ‒20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Cyclin E
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. in vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Type: Primary
Antigen: Cyclin E1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 251-350/410
Host: Rabbit
Isotype: IgG
Reactivity: Human