Specifications
- Antibody type:Primary
- Antigen name:AP2M1 Thr156
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Mouse
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:HA2 50 kDa subunit|mu2 antibody|AP-2 complex subunit mu|Clathrin adaptor complex AP2 mu subunit|Plasma membrane adaptor AP-2 50 kDa protein|Adaptin mu 1|CLAPM1|Clathrin assembly protein complex 2 medium chain|Adaptor protein complex AP 2 subunit mu|Clathrin coat assembly protein AP50|AP-2 mu chain|Clathrin coat adaptor protein AP50|Ap2m1|Clathrin coat-associated protein AP50|Clathrin coat associated protein AP50|Adaptin-mu2|AP2M1_HUMAN|Adapter-related protein complex 2 mu subunit|Clathrin associated/assembly/adaptor protein medium 1|p-AP2M1phospho T156|Adaptor protein complex AP-2 subunit mu|AP2M1 phospho T156|AP 2 mu 2 chain|Adaptor related protein complex 2 mu 1 subunit|AP50
- Modification:Phosphorylation (Thr156)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:50 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human AP2M1 around the phosphorylation site of Thr156
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.
Type: Primary
Antigen: AP2M1 Thr156
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse