Specifications
- Antibody type:Primary
- Antigen name:OLFM3/Optimedin
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rat,Mouse
- Western blot:Yes
- Epitope:101-200/478
- Form:Liquid
- Antigen synonyms:Olfactomedin-3|Olfm3|Olfactomedin related ER localized protein 3|NOELIN3 V2|NOE3_HUMAN|NOELIN3 V6|NOELIN3 V4|Olfactomedin 3|NOELIN3|NOELIN3 V3|Noe3|Olfactomedin3|Optimedin|NOELIN3 V1|Noelin-3|NOELIN3 V5|Noelin 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:52 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human OLFM3/Optimedin
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
OLFM3 is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.
Type: Primary
Antigen: OLFM3/Optimedin
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 101-200/478
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat