- Antibody type:Primary
- Antigen name:CMKLR1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 680
- Flow cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Pig,Human,Rat,Mouse
- Western blot:Yes
- Epitope:151-250/371
- Form:Liquid
- Gene ID:14747
- Antigen synonyms:DEZ|Gpcr27|G-protein coupled receptor DEZ|ChemR23|Cmklr1|Chemokine-like receptor 1|mcmklr1
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:42 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from mouse CMKLR1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular Signalling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism.
Type: Primary
Antigen: CMKLR1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 680
Public Immunogen Range: 151-250/371
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig