Anti-DKK3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
BOSSBS-2686R-A750
: Bioss
- Antibody type:Primary
- Antigen name:DKK3
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Rabbit,Mouse
- Western blot:Yes
- Epitope:31-130/350
- Form:Liquid
- Gene ID:27122
- Antigen synonyms:UNQ258/PRO295|DKK3|Dickkopf-3|RIG|REIC|hDkk-3|Dkk-3|Dickkopf-related protein 3
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:36 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human DKK3
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Type: Primary
Antigen: DKK3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 31-130/350
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rabbit