Specifications
- Antikroppstyp:Primär
- Antikroppsnamn:MCM3
- Klonalitet:Polyclonal
- Konjugation:Alexa Fluor® 750
- Värd:Rabbit
- ImmunKemi:Yes
- ImmunoFluorescens:Yes
- Isotyp:IgG
- Epitop:251-350/808
- Form:Liquid
- Gen-ID:4172
- Antigen synonymer:P1 Protein|MGC1157|P1.h|MCM3 minichromosome maintenance deficient 3|HCC5|Cervical cancer proto oncogene 5|Minichromosome maintenance deficient 3|HCC 5|hRlf beta subunit|RLF subunit beta|Replication licensing factor beta subunit|Human cervical cancer proto oncogene 5|minichromosome maintenance deficient 3|DNA replication licensing factor MCM3|DNA polymerase alpha holoenzyme associated P1|RLFB.|MCM 3|DNA polymerase alpha holoenzyme associated protein P1|P102 protein|DNA replication factor MCM3|Minichromosome maintenance protein 3|P1 h|P1 MCM3|RLF beta subunit
- Modifiering:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molekylvikt:89 kDa
- Förvaringstemperatur:Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Koncentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human MCM3
- Tested applications:ICC
- Rening:Purified by Protein A
- Förpackningstyp:Vial
- Förp.:100 µl
Specifications
About this item
MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Type: Primary
Antigen: MCM3
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 251-350/808
Host: Rabbit
Isotype: IgG
Reactivity: