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Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-1677R-A750
Supplier:  Bioss
Anti-DNA Ligase IV/LIG4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-1677R-A750
Supplier:  Bioss

Specifications

  • Antikroppstyp:
    Primär
  • Antikroppsnamn:
    DNA Ligase IV/LIG4
  • Klonalitet:
    Polyclonal
  • Konjugation:
    Alexa Fluor® 750
  • Värd:
    Rabbit
  • ImmunKemi:
    Yes
  • ImmunoFluorescens:
    Yes
  • Isotyp:
    IgG
  • Reaktivitet:
    Human
  • Western blot:
    Yes
  • Epitop:
    51-150/911
  • Form:
    Liquid
  • Gen-ID:
    3981
  • Antigen synonymer:
    DNA ligase IV|Polydeoxyribonucleotide synthase [ATP] 4|LIG4S|DNA ligase 4|LIG4
  • Modifiering:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
  • Molekylvikt:
    104 kDa
  • Förvaringstemperatur:
    Store at –20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Koncentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human DNA Ligase IV
  • Tested applications:
    ICC
  • Rening:
    Purified by Protein A
  • Förpackningstyp:
    Vial
  • Förp.:
    100 µl

Specifications

About this item

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Type: Primary
Antigen: DNA Ligase IV/LIG4
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 51-150/911
Host: Rabbit
Isotype: IgG
Reactivity: Human