Anti-ATG3 Tyr18 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
BOSSBS-5204R-A750
: Bioss
- Antibody type:Primary
- Antigen name:ATG3 Tyr18
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Western blot:Yes
- Form:Liquid
- Gene ID:64422
- Antigen synonyms:OTTHUMP00000214548|FLJ22125|APG3 autophagy 3 like|Protein PC3-96|2610016C12Rik|OTTHUMP00000214547|ATG3 autophagy related 3 homolog S. cerevisiae|Autophagy-related protein 3|APG3 like|APG3-like|ATG3_HUMAN|ATG 3|PC3 96|hApg3|ATG3 autophagy related 3 homolog|APG3L|DKFZp564M1178|Autophagy related protein 3|Apg3p|Autophagy Apg3p/Aut1p like|Ubiquitin-like-conjugating enzyme ATG3|MGC15201|APG3|Apg 3|ATG3
- Modification:Phosphorylation (Tyr18)
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:36 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic phosphopeptide derived from human ATG3 around the phosphorylation site of Tyr18
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
E2-like enzyme involved in autophagy and mitochondrial homeostasis. catalyses the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). PE-conjugation to ATG8-like proteins is essential for autophagy. Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.
Type: Primary
Antigen: ATG3 Tyr18
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range:
Host: Rabbit
Isotype: IgG
Reactivity: