Specifications
- Antibody type:Primary
- Antigen name:ADRM1
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Epitope:21-120/407
- Form:Liquid
- Gene ID:11047
- Antigen synonyms:Mr 110,000 surface antigen|GP110|Rpn13 homolog|Adhesion-regulating molecule 1|ARM 1|Proteasomal ubiquitin receptor ADRM1|ADRM1_HUMAN|ARM1|Proteasome regulatory particle non-ATPase 13|hRpn13|Rpn13|adhesion regulating molecule 1|Regulatory particle non ATPase 13|proteasome regulatory particle non ATPase 13|ARM-1|ADRM 1|Adrm1|110 kDa cell membrane glycoprotein
- Modification:Unmodified
- Storage buffer:Aqueous buffered solution containing 0,01 M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol
- Molecular weight:42 kDa
- Storage temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human ADRM1
- Tested applications:ICC
- Purification:Purified by Protein A
- Pack type:Vial
- Pk:100 µl
Specifications
About this item
ADRM1 is a 407 amino acid protein that localises to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.
Type: Primary
Antigen: ADRM1
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 21-120/407
Host: Rabbit
Isotype: IgG
Reactivity: