CF® Dye BCN
About this item
CF® Dyes with a BCN group react with azides via a copper-free bioorthogonal reaction to label target molecules for surface staining of live cells or cell extracts. Membrane-permeant CF® Dye BCN conjugates for intracellular labelling reactions are also available.
- Fluorescent labelling of azide groups on target molecules via copper-free bioorthonal chemistry
- Alternative to fluorescently labelled DIBO and DBCO
- Suitable for surface or intracellular labelling of live cells or cell extracts
- Bright, photostable and water-soluble CF® Dyes are excellent options for fluorescent labelling
- Available in several CF® Dye options including membrane-permeant forms for intracellular labelling
CF® Dyes BCN (bicyclo[6.1.0]nonyne) derivatives are alternatives to fluorescently labelled DIBO and DBCO. They react with azides to form 1,2,3-triazole by copper-free bioorthogonal 1,3-dipolar Huisgen cycloaddition. Useful for fluorescent surface labelling of live cells or cell extracts, particularly when there are concerns about native protein function loss with copper. Membrane-permeant CF® Dye BCN options are also available for intracellular labelling reactions.
Available CF® Dye BCN derivatives: CF®405S, CF®405M, CF®488A, CF®568, CF®594, CF®640R, CF®647, CF®680, and CF®680R including membrane-permeant CF®440 BCN, CF®500 BCN, and CF®650 BCN. Biotium's next-generation CF® Dyes were designed to be highly water-soluble with advantages in brightness and photostability compared to Alexa Fluor®, DyLight®, and other fluorescent dyes.
12 Options Available Below
Product Details & Documents
CF® Dyes with a BCN group react with azides via a copper-free bioorthogonal reaction to label target molecules for surface staining of live cells or cell extracts. Membrane-permeant CF® Dye BCN conjugates for intracellular labelling reactions are also available.
- Fluorescent labelling of azide groups on target molecules via copper-free bioorthonal chemistry
- Alternative to fluorescently labelled DIBO and DBCO
- Suitable for surface or intracellular labelling of live cells or cell extracts
- Bright, photostable and water-soluble CF® Dyes are excellent options for fluorescent labelling
- Available in several CF® Dye options including membrane-permeant forms for intracellular labelling
CF® Dyes BCN (bicyclo[6.1.0]nonyne) derivatives are alternatives to fluorescently labelled DIBO and DBCO. They react with azides to form 1,2,3-triazole by copper-free bioorthogonal 1,3-dipolar Huisgen cycloaddition. Useful for fluorescent surface labelling of live cells or cell extracts, particularly when there are concerns about native protein function loss with copper. Membrane-permeant CF® Dye BCN options are also available for intracellular labelling reactions.
Available CF® Dye BCN derivatives: CF®405S, CF®405M, CF®488A, CF®568, CF®594, CF®640R, CF®647, CF®680, and CF®680R including membrane-permeant CF®440 BCN, CF®500 BCN, and CF®650 BCN. Biotium's next-generation CF® Dyes were designed to be highly water-soluble with advantages in brightness and photostability compared to Alexa Fluor®, DyLight®, and other fluorescent dyes.
Product Family Options
Product Information
- Ex/EmPkAvailabilityPrice
- 92114.CF®405M BCN, membrane permeability: ImpermeantCF®405M BCN, membrane permeability: Impermeant408/452 nm0,5 mgLog in for availability1 * 0,5 mg7 125,00 kr
- 92113.CF®405S BCN, membrane permeability: ImpermeantCF®405S BCN, membrane permeability: Impermeant404/431 nm0,5 mgLog in for availability1 * 0,5 mg7 125,00 kr
- 92075.CF®488A BCN, membrane permeability: ImpermeantCF®488A BCN, membrane permeability: Impermeant490/515 nm0,5 mgLog in for availability1 * 0,5 mg7 000,00 kr
- 92076.CF®568 BCN , membrane permeability: ImpermeantCF®568 BCN , membrane permeability: Impermeant562/583 nm0,5 mgLog in for availability1 * 0,5 mg7 000,00 kr
- 92077.CF®594 BCN, membrane permeability: ImpermeantCF®594 BCN, membrane permeability: Impermeant593/614 nm0,5 mgLog in for availability1 * 0,5 mg7 000,00 kr
- 92078.CF®640R BCN, membrane permeability: ImpermeantCF®640R BCN, membrane permeability: Impermeant642/662 nm0,5 mgLog in for availability1 * 0,5 mg7 000,00 kr
- 96059.CF®647 BCN, membrane permeability: ImpermeantCF®647 BCN, membrane permeability: Impermeant650/665 nm0,5 mgLog in for availability1 * 0,5 mg6 700,00 kr
- 96058.CF®680 BCN , membrane permeability: ImpermeantCF®680 BCN , membrane permeability: Impermeant681/698 nm0,5 mgLog in for availability1 * 0,5 mg6 700,00 kr
- 92079.CF®680R BCN , membrane permeability: ImpermeantCF®680R BCN , membrane permeability: Impermeant680/701 nm0,5 mgLog in for availability1 * 0,5 mg7 000,00 kr
- 96070.CF®440 BCN , membrane permeability: PermeantCF®440 BCN , membrane permeability: Permeant440/515 nm0,5 mgLog in for availability1 * 0,5 mg6 700,00 kr
- 96026.CF®500 BCN, membrane permeability: PermeantCF®500 BCN, membrane permeability: Permeant502/511 nm0,5 mgLog in for availability1 * 0,5 mg6 900,00 kr
- 96027.CF®650 BCN, membrane permeability: PermeantCF®650 BCN, membrane permeability: Permeant653/673 nm0,5 mgLog in for availability1 * 0,5 mg6 900,00 kr
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