Bond Elut C18 OH is unendcapped, offering tightly controlled silanol activity to support fractionation. C18 OH delivers enhanced retention of polar analytes.

• Silanol activity permits metabolite fractionation
• Tight QC tolerances deliver batch-to-batch reproducibility
• 150 Å pore size expands retention window to higher molecular weight compounds

It is a nonendcapped version of the octadecyl bonded phases that enables the silanols on the silica surface to be more active. This low-load C18 has well-controlled silanol activity that permits the fractionation of metabolites and enhances retention of basic compounds compared to an endcapped C18. The pore size makes it a good choice for peptide extraction.