- Pk:10 µG
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Human
- Tag sequence:DDDDK Tag
- Storage conditions:Stable for at least 6 months after receipt when stored at −20 °C.
- Gene ID:5176
- Protein synonyms:Serpin F1|EPC-1|Pigment Epithelium-derived Factor|Cell Proliferation-inducing Gene 35 Protein
- Protein/peptide name:PEDF
- Purity:>95% (SDS-PAGE)
- Sequence:20-418
- Formulation:Lyophilized, Contains PBS.
Pigment epithelium-derived factor (PEDF) is a 47 kDa secreted glycoprotein that belongs to the non-inhibitory serpin family group. PEDF is widely expressed in adult and foetal tissues, including brain, spinal cord, plasma, bone, prostate, pancreas, heart and lung. PEDF acts as an angiogenesis inhibitor with neurotrophic, immunomodulation and antitumor properties. It functions as anti-angiogenic agent by counterbalancing the proangiogenic effect of VEGF. PEDF is one of the most abundant proteins released by adipocytes and induces insulin resistance in adipocytes and human skeletal muscle cells. Recently, it has been reported that PEDF is sufficient to maintain the self-renewal of pluripotent human embryonic stem cells.
Fusion-Tag: DDDDK Tag
This recombinant proteins is for research use only.