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Human recombinant LYPD3 (from cells)
Human recombinant LYPD3 (from cells)
Catalog # PRSI91-440
Supplier:  ProSci Inc.
CAS Number:  
Human recombinant LYPD3 (from cells)
Catalog # PRSI91-440
Supplier:  ProSci Inc.
CAS Number:  

Specifications

  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Source:
    Cells
  • Species:
    Human
  • Tag sequence:
    C-6 His tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    Ly6/PLAUR Domain-Containing Protein 3|C4.4A|Matrigel-Induced Gene C4 Protein|MIG-C4|GPI-Anchored Metastasis-Associated Protein C4.4A Homolog|LYPD3
  • Protein/peptide name:
    LYPD3
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    27.89 kD
  • Sequence:
    Leu31-His286
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
  • Tested applications:
    Bioassay

Specifications

About this item

Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.

  • This recombinant protein can be used for biological assays. For research use only.

Fusion-Tag: C-6 His tag